Ursocholic acid (Synonyms: 7β-Hydroisocholic Acid, 7-Epichoic Acid, 3α,7β,12α-Trihydroxy-5β-cholanoic Acid, UCA) |
| Katalog-Nr.GC33799 |
UrsocholsÄure, eine GallensÄure, die vorwiegend in der Galle von SÄugetieren vorkommt, wird bei MÄusen durch die Darmflora in DesoxycholsÄure umgewandelt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2955-27-3
Sample solution is provided at 25 µL, 10mM.
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Ursocholic acid, a bile acid found predominantly in bile of mammals, is an inhibitor of 7α-hydroxysteroid dehydrogenase and hepatocyte nuclear factor 1α.
[1]. MacDonald IA, et al. Formation of ursodeoxycholic acid from chenodeoxycholic acid by a 7 beta-hydroxysteroid dehydrogenase-elaborating Eubacterium aerofaciens strain cocultured with 7 alpha-hydroxysteroid dehydrogenase-elaborating organisms. Appl Environ Microbiol. 1982 Nov;44(5):1187-95. [2]. Lee HI, et al. Ursodeoxycholic acid, an inhibitor of hepatocyte nuclear factor 1α, did not increase the systemic exposure of pitavastatin. Int J Clin Pharmacol Ther. 2014 Nov;52(11):981-5.
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