GLPBio

Dec-9-yn-1-amine

Catalog No.: GC81080Purity:>99.00%
COASDSData Sheet
Dec-9-yn-1-amine is a PROTAC linker can be used in the synthesis of PROTACs [1].

Products are for research use only. Not for human use. We do not sell to patients.

Dec-9-yn-1-amine
Cas No.: 1027371-95-4
5mgIn Stock
$107.00
1
10mgIn Stock
$172.00
1
25mgIn Stock
$344.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Dec-9-yn-1-amine is a PROTAC linker can be used in the synthesis of PROTACs [1].

In Vitro, PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

References:
[1]. Yim H, et al. Discovery of KRAS-G12D degraders via exploration of various E3 ligases. Eur J Med Chem. 2026;307:118635.

Product Documents

Purity:>99.00%Appearance:Liquid (Density: 0.846±0.06 g/cm 3 )
COASDSData Sheet

Chemical Properties

CAS No.
1027371-95-4
Molecular Formula
C10H19N
Molecular Weight
153.26
Storage
Store at 4°C, protect from light, stored under nitrogen
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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