Desmethyl-VS-5584 hydrochloride

Name: Desmethyl-VS-5584 hydrochloride
Brand: GlpBio
SKU: GC72768
Availability: InStock

Catalog No.: GC72768Purity:>98.00%Synonyms: Desmethyl-SB2343 hydrochloride

Desmethyl-VS-5584 hydrochloride is a dimethyl analog of VS-5584, a potent and selective dual mTOR/PI3K inhibitor, with a pyridine[2,3-d]pyrimidine structure.

Products are for research use only. Not for human use. We do not sell to patients.

1 mgIn Stock

$80.00

5 mgIn Stock

$158.00

10 mgIn Stock

$253.00

25 mgIn Stock

$493.00

Pack Size	Price	Availability	Quantity
1 mg	$80.00	In Stock	1
5 mg	$158.00	In Stock	1
10 mg	$253.00	In Stock	1
25 mg	$493.00	In Stock	1

Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.

Nature
641, 529–536 (2025)
Nature
628, 630–638 (2024)
Nature
632, 686–694 (2024)
Nature
618, 1017–1023 (2023)
Nature
610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
Science
388(6745) (2025)
Science
387(6739) (2025)
Science
387(6734) (2025)
Cell Research
35, 97–116 (2025)
Cell Research
34, 683–706 (2024)
Cell Research
33, 273–287 (2023)
Cell Research
33, 546–561 (2023)
Cell Research
33, 904–922 (2023)
Cell Research
31, 1291–1307 (2021)

Description

Desmetl-VS-5584 drochloride is a dimetl analog of VS-5584, a potent and selective mTOR/PI3KDual inhibitor, with a pyridine[2,3-d]pyrimidine structure.

References:
[1]. Hart S, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013;12(2):151-161.

Product Documents

Batch:Purity:>98.00%Appearance:A solid

COA SDS Data Sheet

Chemical Properties

Synonyms

Desmethyl-SB2343 hydrochloride

Molecular Formula

C₁₆H₂₂Cl₂N₈O

Molecular Weight

413.3

Solubility

DMSO : 2.67 mg/mL (6.46 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

Storage

4°C, sealed storage, away from moisture

General tips

Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.

Shipping Condition

Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

Mass

Volume

Concentration

Molecular Weight

g/mol

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