GLPBio

Diaziquone

Catalog No.: GC72908Purity:>98.00%Synonyms: NSC 182986
Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity.

Products are for research use only. Not for human use. We do not sell to patients.


Diaziquone
Cas No.: 57998-68-2
1 mgIn Stock
$132.00
1
5 mgIn Stock
$328.00
1
10 mgIn Stock
$479.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity.

Diaziquone (6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m) has a broad range of activity of diaziquone against primary nervous system tumors and has enhancement effect combined with either 1,3-bis(2-chloroetl)-1-nitrosourea or procarbazine in atmic mice[1].

References:
[1]. S C Schold Jr, et al. Treatment of human glioma and medulloblastoma tumor lines in atmic mice with diaziquone and diaziquone-based drug combinations. Cancer Res. 1984 Jun;44(6):2352-7.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
57998-68-2
Synonyms
NSC 182986
Molecular Formula
C16H20N4O6
Molecular Weight
364.35
Solubility
DMSO : 125 mg/mL (343.08 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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