Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant.
DR 2313
Catalog No.: GC12680Purity:>98.50%
A PARP inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 284028-90-6
5mgIn Stock
$114.00
1
10mgIn Stock
$188.00
1
25mgIn Stock
$354.00
1
50mgIn Stock
$147.00
1
100mgIn Stock
$213.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $114.00 | In Stock | 1 | |
| 10mg | $188.00 | In Stock | 1 | |
| 25mg | $354.00 | In Stock | 1 | |
| 50mg | $147.00 | In Stock | 1 | |
| 100mg | $213.00 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.50%Appearance:A solid
Chemical Properties
CAS No.
284028-90-6
Chemical Name
2-methyl-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
SMILES
CC1=NC(=O)C2=C(N1)CCSC2
Molecular Formula
C8H10N2OS
Molecular Weight
182.24
Solubility
≥ 83.3mg/mL in DMSO, ≥ 9.1mg/mL in Water
Storage
Store at 4°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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