Dynarrestin |
| Catalog No.GC50486 |
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2222768-84-3
Sample solution is provided at 25 µL, 10mM.
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Dynein inhibitor. Inhibits hedgehog signaling in vitro (IC50 = 0.22 μM). Exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Inhibits tumor cell proliferation in a mouse medulloblastoma model.
Höing et al (2018) Dynarrestin, a novel inhibitor or cytoplasmic dynein. Cell Chem.Biol. 25 357 PMID:29396292
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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