EAAT2
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Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.
The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.
Products Related to EAAT2(6)
- GC38524WAY-213613 hydrochlorideCAS: 2450268-84-3Purity: >98.50%
WAY-213613 (hydrochloride) is a potent and selective human EAAT2 inhibitor.
- GC64288EAAT2 activator 1CAS: 892415-28-0Purity: >98.00%
EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2).
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10875 | LDN 212320 | 894002-50-7 | >98.00% | |
increases expression of glutamate transporter EAAT2 | ||||
| GC13659 | WAY 213613 | 868359-05-1 | >99.00% | |
EAAT2 (GLT-1) inhibitor | ||||
| GC31075 | GT 949 | 460330-27-2 | >99.50% | |
A positive allosteric modulator of EEAT2 | ||||
| GC38472 | DL-TBOA | 205309-81-5 | >98% | |
An EAAT inhibitor | ||||
| GC38524 | WAY-213613 hydrochloride | 2450268-84-3 | >98.50% | |
WAY-213613 (hydrochloride) is a potent and selective human EAAT2 inhibitor. | ||||
| GC64288 | EAAT2 activator 1 | 892415-28-0 | >98.00% | |
EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). | ||||