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Membrane Transporter/Ion Channel

Products for  Membrane Transporter/Ion Channel

  1. Cat.No. Product Name Information
  2. GC49097 α-Conotoxin AuIB (trifluoroacetate salt)

    GCCSYPPCFATNPDC

    A conotoxin and an antagonist of α3β4 subunit-containing nAChRs α-Conotoxin AuIB (trifluoroacetate salt)  Chemical Structure
  3. GC49140 α-Conotoxin ImI (trifluoroacetate salt)

    α-CTx ImI, GCCSDPRCAWRC

    A conotoxin and an antagonist of α7 nAChRs α-Conotoxin ImI (trifluoroacetate salt)  Chemical Structure
  4. GC63269 α-Conotoxin PIA TFA α-Conotoxin PIA TFA  Chemical Structure
  5. GC63723 α-Conotoxin PnIA TFA α-Conotoxin PnIA TFA  Chemical Structure
  6. GC10873 α-Spinasterol

    Bessisterol, Hitodesterol

    TRPV1 antagonist α-Spinasterol  Chemical Structure
  7. GC70179 α7 Nicotinic receptor agonist-1

    Alpha-7 Nicotinic receptor agonist-1 (Preparation 5) is an alpha-7 nAChR agonist. It can be used for research on psychiatric disorders such as schizophrenia, mania or bipolar disorder, and anxiety disorders, as well as intellectual disabilities such as Alzheimer's disease, learning deficits, cognitive impairments, attention deficits, memory loss, Lewy body dementia and attention deficit hyperactivity disorder.

    α7 Nicotinic receptor agonist-1  Chemical Structure
  8. GC48998 β-Defensin-1 (human) (trifluoroacetate salt)

    hBD-1

    An antimicrobial peptide β-Defensin-1 (human) (trifluoroacetate salt)  Chemical Structure
  9. GC38010 γ-Aminobutyric acid γ-Aminobutyric acid  Chemical Structure
  10. GC64508 γ-Aminobutyric acid-d6

    γ-Aminobutyric acid-d6 (4-Aminobutyric acid-d6) is the deuterium labeled γ-Aminobutyric acid.

    γ-Aminobutyric acid-d6  Chemical Structure
  11. GC48313 γ-Lindane An insecticide and GABAA receptor antagonist γ-Lindane  Chemical Structure
  12. GC15513 ω-Agatoxin IVA ω-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA  Chemical Structure
  13. GC12608 ω-Agatoxin TK ω-Agatoxin TK, a peptidyl toxin of the venom of Agelenopsis aperta, is a potent and selective P/Q type Ca2+ channel blocker. ω-Agatoxin TK  Chemical Structure
  14. GC13886 ω-Conotoxin GVIA ω-Conotoxin GVIA is a cone snail toxin that selectively blocks N-type channels in neurons . ω-Conotoxin GVIA  Chemical Structure
  15. GC18070 ω-Conotoxin MVIIC wide spectrum blocker of N, P and Q type calcium channels ω-Conotoxin MVIIC  Chemical Structure
  16. GC31248 β-Amino Acid Imagabalin Hydrochloride (PD-0332334)

    PD-0332334

    β-Amino Acid Imagabalin Hydrochloride (PD-0332334) (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel. β-Amino Acid Imagabalin Hydrochloride (PD-0332334)  Chemical Structure
  17. GC11449 β-CCB

    benzodiazepine receptor ligand

    β-CCB  Chemical Structure
  18. GC18033 γDGG γDGG is a competitive AMPA receptor blocker. γDGG  Chemical Structure
  19. GC70188 ω-Agatoxin IVA TFA

    ω-Agatoxin IVA TFA is an effective selective blocker of P/Q-type Ca2+ (Cav2.1) channels, with IC50 values of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA TFA (IC50, 30-225 nM) inhibits high potassium-induced glutamate release and calcium influx. It also blocks the release of serotonin and adrenaline induced by high potassium, without affecting L-type or N-type calcium channels.

    ω-Agatoxin IVA TFA  Chemical Structure
  20. GC62067 ω-Conotoxin GVIA TFA ω-Conotoxin GVIA TFA  Chemical Structure
  21. GA24016 ω-Conotoxin MVIIA ω-Conotoxin MVIIA (SNX-111), a peptide, is a potent and selective block of N-type calcium channels antagonist. ω-Conotoxin MVIIA  Chemical Structure
  22. GC64899 ω-Conotoxin MVIIC TFA ω-Conotoxin MVIIC TFA  Chemical Structure
  23. GC49296 τ-Fluvalinate

    tau-Fluvalinate

    A pyrethroid acaricide τ-Fluvalinate  Chemical Structure
  24. GC10237 (±)-1-(1,2-Diphenylethyl)piperidine maleate NMDA receptor antagonist (±)-1-(1,2-Diphenylethyl)piperidine maleate  Chemical Structure
  25. GC14410 (±)-Epibatidine

    CMI 545

    nicotinic agonist (±)-Epibatidine  Chemical Structure
  26. GC11138 (±)-HIP-A excitatory amino acid transporter (EAAT) blocker (±)-HIP-A  Chemical Structure
  27. GC13735 (±)-HIP-B

    excitatory amino acid transporter (EAAT) blocker

    (±)-HIP-B  Chemical Structure
  28. GC45985 (±)-Indoxacarb

    DPX-JW062, DPX-MP062

    A broad-spectrum insecticide (±)-Indoxacarb  Chemical Structure
  29. GC14834 (±)-Nipecotic acid

    (±)-Nipecotic Acid, (R,S)-Nipecotic Acid, 3-Piperidine Carboxylic Acid, DL-Piperidine 3-Carboxylic Acid

    GABA uptake inhibitor (±)-Nipecotic acid  Chemical Structure
  30. GC41676 (±)-Nornicotine

    DL-Nornicotine, (R,S)-Nornicotine

    (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine  Chemical Structure
  31. GC49482 (±)-Nornicotine-d4

    DL-Nornicotine-d4, (R,S)-Nornicotine-d4

    An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4  Chemical Structure
  32. GC41677 (±)-SDZ-201 106

    DPI 201-106

    (±)-SDZ-201 106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. (±)-SDZ-201 106  Chemical Structure
  33. GC11982 (±)-threo-3-Methylglutamic acid glutamate transport blocker (±)-threo-3-Methylglutamic acid  Chemical Structure
  34. GC40466 (±)11(12)-EET

    (±)11,12-EpETrE

    (±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.

    (±)11(12)-EET  Chemical Structure
  35. GC40434 (±)16-HETE

    (±)16-Hydroxyeicosatetraenoic Acid

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE  Chemical Structure
  36. GC40270 (±)5(6)-DiHET

    (±)5,6-DiHETrE

    5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.

    (±)5(6)-DiHET  Chemical Structure
  37. GC40438 (±)5(6)-EET

    (±)5,6EpETrE

    5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. (±)5(6)-EET  Chemical Structure
  38. GN10612 (+)- Praeruptorin C (+)- Praeruptorin C  Chemical Structure
  39. GC34954 (+)-Borneol

    D-Borneol, (1R)-(+)-Borneol, (+)-endo-Borneol

    (+)-Borneol  Chemical Structure
  40. GC30933 (+)-Kavain

    Kawain, NSC 112162

    An Analytical Reference Standard

    (+)-Kavain  Chemical Structure
  41. GC40808 (+)-Menthol

    D-Menthol

    (+)-Menthol is a monoterpene alcohol that has been found in Cannabis and has antifungal activity. (+)-Menthol  Chemical Structure
  42. GC16616 (+)-MK 801

    Dizocilpine maleate;Dizocilpine hydrogen maleate;(+)-MK 801;MK 801

    (+)-MK 801  Chemical Structure
  43. GC11025 (+)-MK 801 Maleate

    Dizocilpine Maleate

    (+)-MK 801 Maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. (+)-MK 801 Maleate  Chemical Structure
  44. GC32130 (+)-SJ733 (SJ000557733)

    SJ000557733

    (+)-SJ733 (SJ000557733) is an anti-malaria agent which can also inhibit Na+-ATPase PfATP4. (+)-SJ733 (SJ000557733)  Chemical Structure
  45. GC34959 (+)-Sparteine

    Pachycarpin, Pachycarpine

    (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine  Chemical Structure
  46. GC38677 (-)-α-Pinene

    NSC 7727

    (-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site. (-)-α-Pinene  Chemical Structure
  47. GC31084 (-)-(S)-B-973B (-)-(S)-B-973B  Chemical Structure
  48. GC10065 (-)-Bicuculline methiodide GABAA receptor antagonist (-)-Bicuculline methiodide  Chemical Structure
  49. GC16857 (-)-Bicuculline methobromide (-)-Bicuculline methobromide  Chemical Structure
  50. GC15636 (-)-Bicuculline methochloride (-)-Bicuculline methochloride  Chemical Structure
  51. GC13430 (-)-Blebbistatin

    (S)Blebbistatin

    (-)-Blebbistatin  Chemical Structure
  52. GC63940 (-)-Denudatin B (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B  Chemical Structure
  53. GC14157 (-)-Lobeline hydrochloride

    (–)-α-Lobeline, VUF 10751

    nicotinic receptor partial agonist (-)-Lobeline hydrochloride  Chemical Structure
  54. GC34951 (-)-Menthol

    L-Menthol, (1R,2S,5R)-(-)-Menthol, NSC 62788

    A monoterpene with diverse biological activities (-)-Menthol  Chemical Structure
  55. GC15270 (-)-MK 801

    (-)-Dizocilpine Maleate

    (-)-MK 801 ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-MK 801  Chemical Structure
  56. GN10445 (-)-pareruptorin A (-)-pareruptorin A  Chemical Structure
  57. GC30889 (-)-Securinine

    NSC 107413, L-Securinine

    An alkaloid (-)-Securinine  Chemical Structure
  58. GC34952 (-)-Sparteine sulfate pentahydrate (-)-Sparteine sulfate pentahydrate  Chemical Structure
  59. GC14484 (-)-Xestospongin C

    XeC, Araguspongine E

    IP3-dependent Ca2+ release inhibitor

    (-)-Xestospongin C  Chemical Structure
  60. GC14044 (-)-[3R,4S]-Chromanol 293B (-)-[3R,4S]-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-[3R,4S]-Chromanol 293B  Chemical Structure
  61. GC64062 (1R,2R)-ML-SI3

    (1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 (IC50 values of 1.6 and 2.3 μM) and a weak inhibitor (IC50 12.5 μM) of TRPML3.

    (1R,2R)-ML-SI3  Chemical Structure
  62. GC16915 (2R,3S)-Chlorpheg NMDA receptor antagonist (2R,3S)-Chlorpheg  Chemical Structure
  63. GC50536 (2R/S)-6-PNG

    (±)-6-PN

    CaV3.2 blocker; active in vivo (2R/S)-6-PNG  Chemical Structure
  64. GC66255 (E)-3,4,5-Trimethoxycinnamic acid

    TMCA

    (E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABAA/BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT2C and 5-HT1A receptor, with IC50 values of 2.5 and 7.6 μM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy. (E)-3,4,5-Trimethoxycinnamic acid  Chemical Structure
  65. GC62560 (E/Z)-Sivopixant

    (E/Z)-S-600918

    (E/Z)-Sivopixant ((E/Z)-S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM. (E/Z)-Sivopixant  Chemical Structure
  66. GC13895 (R)-(+)-Bay K 8644

    NI 105, R 4407

    L-type Ca2+-channel blocker (R)-(+)-Bay K 8644  Chemical Structure
  67. GC14085 (R)-(+)-HA-966 NMDA receptor antagonist/partial agonist (R)-(+)-HA-966  Chemical Structure
  68. GC40696 (R)-(+)-Pulegone

    NSC 15334, D-Pulegone

    (R)-(+)-Pulegone, the major chemical constituent of Calamintha nepeta (L. (R)-(+)-Pulegone  Chemical Structure
  69. GC10168 (R)-4-Carboxyphenylglycine NMDA receptor antagonist (R)-4-Carboxyphenylglycine  Chemical Structure
  70. GC11071 (R)-AMPA inactive enantiomer of AMPA (R)-AMPA  Chemical Structure
  71. GC14111 (R)-baclofen GABA receptor agonist (R)-baclofen  Chemical Structure
  72. GC34986 (R)-Baclofen hydrochloride

    (R)-Baclofen

    (R)-Baclofen hydrochloride (Arbaclofen hydrochloride) is a selective GABAB receptor agonist. (R)-Baclofen hydrochloride  Chemical Structure
  73. GC31665 (R)-BPO-27 (R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR?inhibitor with an?IC50 of 4 nM. (R)-BPO-27  Chemical Structure
  74. GC14236 (R)-CPP NMDA antagonist (R)-CPP  Chemical Structure
  75. GC69812 (R)-Elexacaftor

    (R)-VX-445

    (R)-Elexacaftor is the enantiomer of Elexacaftor (Compound 1) and comes from Compound 37 in patent WO2018107100A1. It is a corrector of cystic fibrosis transmembrane conductance regulator (CFTR), with an EC50 value of 0.29 uM for CFTR dF508.

    (R)-Elexacaftor  Chemical Structure
  76. GC62739 (R)-Funapide

    (R)-TV 45070; (R)-XEN402

    (R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. (R)-Funapide  Chemical Structure
  77. GC61847 (R)-Lanicemine (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. (R)-Lanicemine  Chemical Structure
  78. GC66419 (R)-Lercanidipine-d3 hydrochloride (R)-lercanidipine D3 (hydrochloride) is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride), the R-enantiomer of Lercanidipine, is a calcium channel blocker. (R)-Lercanidipine-d3 hydrochloride  Chemical Structure
  79. GC68475 (R)-Nicardipine

    (R)-YC-93 free base

    (R)-Nicardipine  Chemical Structure
  80. GC41719 (R)-nitro-Blebbistatin

    R(-)7Desmethyl8nitro Blebbistatin

    (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin  Chemical Structure
  81. GC67767 (R)-Olacaftor

    (R)-VX-440

    (R)-Olacaftor  Chemical Structure
  82. GC62513 (R)-Posenacaftor sodium

    (R)-PTI-801 sodium

    (R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. (R)-Posenacaftor sodium  Chemical Structure
  83. GC69839 (R)-Tegoprazan

    (R)-CJ-12420; (R)-RQ-00000004

    (R)-Tegoprazan ((R)-CJ-12420; example 3) is a benzimidazole derivative and an effective inhibitor of gastric H+/K+-ATPase. Its IC50 for canine kidney Na+/K+-ATPase is 98 nM. (R)-Tegoprazan has potential in the research of gastrointestinal diseases.

    (R)-Tegoprazan  Chemical Structure
  84. GC60407 (R)-Verapamil D7 hydrochloride

    (R)-(+)-Verapamil D7 hydrochloride

    (R)-Verapamil D7 hydrochloride ((R)-(+)-Verapamil D7 hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer drugs. (R)-Verapamil D7 hydrochloride  Chemical Structure
  85. GC60408 (R)-Verapamil hydrochloride (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer drugs. (R)-Verapamil hydrochloride  Chemical Structure
  86. GC63511 (Rac)-CP-601927 hydrochloride (Rac)-CP-601927 hydrochloride is the racemate of CP-601927. (Rac)-CP-601927 hydrochloride  Chemical Structure
  87. GC61446 (Rac)-Lanicemine (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. (Rac)-Lanicemine  Chemical Structure
  88. GC61873 (Rac)-MEM 1003 (Rac)-MEM 1003 is the racemate of MEM 1003. (Rac)-MEM 1003  Chemical Structure
  89. GC60413 (Rac)-NMDAR antagonist 1 (Rac)-NMDAR antagonist 1 is the racemate of NMDAR antagonist 1. (Rac)-NMDAR antagonist 1  Chemical Structure
  90. GC12488 (RS)-(Tetrazol-5-yl)glycine

    Tet-Glycine, LY285265, DL-(Tetrazol-5-yl)glycine

    NMDA receptor agonist (RS)-(Tetrazol-5-yl)glycine  Chemical Structure
  91. GC13631 (RS)-AMPA AMPA agonist (RS)-AMPA  Chemical Structure
  92. GC13032 (RS)-AMPA hydrobromide AMPAR agonist (RS)-AMPA hydrobromide  Chemical Structure
  93. GC62746 (RS)-AMPA monohydrate

    (±)-AMPA monohydrate

    (RS)-AMPA ((±)-AMPA) monohydrate is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA monohydrate  Chemical Structure
  94. GC10476 (RS)-CPP NMDA antagonist (RS)-CPP  Chemical Structure
  95. GC11889 (S)-(-)-5-Fluorowillardiine AMPA receptor agonist (S)-(-)-5-Fluorowillardiine  Chemical Structure
  96. GC34998 (S)-(-)-5-Fluorowillardiine hydrochloride

    (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride

    (S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist. (S)-(-)-5-Fluorowillardiine hydrochloride  Chemical Structure
  97. GC15768 (S)-(-)-5-Iodowillardiine hGluR5 kainate receptor agonist (S)-(-)-5-Iodowillardiine  Chemical Structure
  98. GC14229 (S)-(-)-Bay K 8644 L-type Ca2+-channel activator (S)-(-)-Bay K 8644  Chemical Structure
  99. GC63321 (S)-(-)-Felodipine-d5 (S)-(-)-Felodipine-d5  Chemical Structure
  100. GC10370 (S)-(-)-HA-966 NMDA receptor antagonist (S)-(-)-HA-966  Chemical Structure
  101. GC64735 (S)-(-)-Levamisole (S)-(-)-Levamisole (Levamisole), an anthelmintic agent with immunomodulatory properties. (S)-(-)-Levamisole  Chemical Structure

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