GLPBio

Eliapixant

Catalog No.: GC62950Purity:>99.50%
COASDSData Sheet
Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM.

Products are for research use only. Not for human use. We do not sell to patients.

Eliapixant
Cas No.: 1948229-21-7
10mM (in 1mL DMSO)In Stock
$266.00
1
1mgIn Stock
$120.00
1
5mgIn Stock
$252.00
1
10mgIn Stock
$360.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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Description

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Eliapixant can be used for the research of coughs and diabetes complications[1].

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.
[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1948229-21-7
Molecular Formula
C22H21F3N4O3S
Molecular Weight
478.49
Solubility
DMSO : 33.33 mg/mL (69.66 mM; ultrasonic and warming and heat to 60°C)
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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