P2X purinergic receptor
P2X purinergic receptor is a famliy of ATP-gated cation channels. It is widely distributed in the body and paly an important role in regulation of synaptic transmission, vascular endothelium and nociception etc.
Products Related to P2X purinergic receptor(69)
- GC12339IvermectinCAS: 70288-86-7Purity: >98.00%
Ivermectin is a macrolide endectocide with activity against both endoparasites and ectoparasites.
- GC12421Brilliant blue G-250CAS: 6104-58-1Purity: >92.00%
Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation.
- GC12574ATPγS tetralithium saltCAS: 93839-89-5Purity: >90.00%
ATPγS (tetralithium salt) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A.
- GC13733A 438079 hydrochlorideCAS: 899431-18-6Purity: >99.50%
An antagonist of the nucleotide receptor P2X7
- GC14207GW791343 HClCAS: 309712-55-8Purity: >98%
GW791343 HCl is a potent human P2X7 receptor negative allosteric modulator (exhibits species-specific activity), produces a non-competitive antagonist effect on human P2X7 receptor, with a pIC50 of 6.9-7.2.
- GC154162-Methylthioadenosine triphosphate tetrasodium saltCAS: 100020-57-3Purity: >98%
2-Methylthioadenosine triphosphate tetrasodium salt is a non-specific P2-receptor agonist.
- GC15898BzATP triethylammonium saltCAS: 112898-15-4Purity: >99.50%
BzATP triethylammonium salt is a potent adenosine triphosphate (ATP) analog that primarily acts as a purinergic P2X receptor (EC 50 ：rat P2X7 = 3.6μM；mouse P2X7 = 285μM).
- GC15988KN-92 hydrochlorideCAS: 1431698-47-3Purity: >99.50%
KN-92 hydrochloride is an inactive analogue of KN-93 and can be converted to KN-93 by modification.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC12339 | Ivermectin | 70288-86-7 | >98.00% | |
Ivermectin is a macrolide endectocide with activity against both endoparasites and ectoparasites. | ||||
| GC10152 | RO-3 | 1026582-88-6 | >98% | |
homomeric P2X3 and heteromeric P2X2/3 receptor antagonist | ||||
| GC10411 | MRS 2219 | 14141-47-0 | >98% | |
P2X1 receptor potentiator | ||||
| GC10990 | iso-PPADS tetrasodium salt | 207572-67-6 | >98% | |
P2 purinoceptors antagonist, specific | ||||
| GC11109 | ATP disodium salt | 987-65-5 | >99.00% | |
P2 purinoceptor agonist | ||||
| GC11216 | Ro 0437626 | 134362-79-1 | >98% | |
P2X1 purinergic receptor antagonist | ||||
| GC11289 | NF 023 | 104869-31-0 | >98% | |
NF 023 is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively. | ||||
| GC11326 | NF 449 | 627034-85-9 | >98.00% | |
NF 449 is an efficient purine receptor antagonist, showing high selectivity for P2X 1 (IC 50 values for rP2X 1 , rP2X 1+5 , rP2X 2+3 , and rP2X 3 receptors are 0.28, 0.69, 120, and 1820nM, respectively). | ||||
| GC11682 | TC-P 262 | 873398-67-5 | >98% | |
P2X3 and P2X2/3 receptor antagonist | ||||
| GC11842 | A-740003 | 861393-28-4 | >98.00% | |
A-740003 is an orally active P2X7 receptor antagonist (IC 50 =40nM). | ||||
| GC12421 | Brilliant blue G-250 | 6104-58-1 | >92.00% | |
Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. | ||||
| GC12574 | ATPγS tetralithium salt | 93839-89-5 | >90.00% | |
ATPγS (tetralithium salt) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. | ||||
| GC13224 | NF 110 | 111150-22-2 | >98% | |
P2X3 antagonist | ||||
| GC13584 | Purotoxin 1 | 1396322-38-5 | >98% | |
P2X3 receptor modulator | ||||
| GC13733 | A 438079 hydrochloride | 899431-18-6 | >99.50% | |
An antagonist of the nucleotide receptor P2X7 | ||||
| GC13943 | 5-BDBD | 768404-03-1 | >98.00% | |
5-BDBD is a potent and selective P2X4 receptor antagonist with an IC 50 value of 0.5-0.75μM, capable of inhibiting rP2X4R-mediated currents. | ||||
| GC14202 | KN-62 | 127191-97-3 | >99.00% | |
KN-62 is a selective calmodulin-dependent protein kinase II (CaMKII) inhibitor and also a potent non-competitive P2X7 receptor antagonist. | ||||
| GC14207 | GW791343 HCl | 309712-55-8 | >98% | |
GW791343 HCl is a potent human P2X7 receptor negative allosteric modulator (exhibits species-specific activity), produces a non-competitive antagonist effect on human P2X7 receptor, with a pIC50 of 6.9-7.2. | ||||
| GC14992 | NF 279 | 202983-32-2 | >98% | |
P2X1 antagonist | ||||
| GC15416 | 2-Methylthioadenosine triphosphate tetrasodium salt | 100020-57-3 | >98% | |
2-Methylthioadenosine triphosphate tetrasodium salt is a non-specific P2-receptor agonist. | ||||
| GC15434 | A 839977 | 870061-27-1 | >98.00% | |
P2X7 antagonist,potent and selective | ||||
| GC15898 | BzATP triethylammonium salt | 112898-15-4 | >99.50% | |
BzATP triethylammonium salt is a potent adenosine triphosphate (ATP) analog that primarily acts as a purinergic P2X receptor (EC 50 ：rat P2X7 = 3.6μM；mouse P2X7 = 285μM). | ||||
| GC15988 | KN-92 hydrochloride | 1431698-47-3 | >99.50% | |
KN-92 hydrochloride is an inactive analogue of KN-93 and can be converted to KN-93 by modification. | ||||
| GC16330 | Ro 51 | 1050670-85-3 | >98% | |
dual P2X3 and P2X2/3 antagonist | ||||