EZH2
EZH2 (enhancer of zeste homolog 2) is a polycomb group protein and histone methyltrasferase that associated with transcriptional repression. It catalyzes trimethylation of H3K27me3 (histone H3 lysine 27) as a catalytic subunit of PRC2 (polycomb repressive complex 2).
Products Related to EZH2(10)
- GC131453-Deazaneplanocin,DZNepCAS: 102052-95-9Purity: >98.00%
An inhibitor of lysine methyltransferase EZH2
- GC179073-Deazaneplanocin A (DZNep) hydrochlorideCAS: 120964-45-6Purity: >99.50%
3-Deazaneplanocin A (DZNep) hydrochloride is an adenosine analogue and is a competitive S-adenosylhomocysteine hydrolase inhibitor with a Ki of 50 pM in cell-free tests.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC11414 | GSK503 | 1346572-63-1 | >99.50% | |
EZH2 inhibitor | ||||
| GC13145 | 3-Deazaneplanocin,DZNep | 102052-95-9 | >98.00% | |
An inhibitor of lysine methyltransferase EZH2 | ||||
| GC13878 | EPZ005687 | 1396772-26-1 | >99.00% | |
A potent, selective inhibitor of EZH2 | ||||
| GC15783 | GSK126 | 1346574-57-9 | >98.00% | |
GSK126 (GSK2816126A, GSK2816126) is a highly selective EZH2 methyltransferase inhibitor with IC 50 12.6-17.4nM in vitro (MM cells), and IC 50 9.9nM in vivo (Male *ApoE-/-* mice) . | ||||
| GC17534 | GSK343 | 1346704-33-3 | >98.00% | |
A selective, cell-permeable EZH2 inhibitor | ||||
| GC17907 | 3-Deazaneplanocin A (DZNep) hydrochloride | 120964-45-6 | >99.50% | |
3-Deazaneplanocin A (DZNep) hydrochloride is an adenosine analogue and is a competitive S-adenosylhomocysteine hydrolase inhibitor with a Ki of 50 pM in cell-free tests. | ||||
| GC14756 | EI1 | 1418308-27-6 | >99.50% | |
EZH2 inhibitor | ||||
| GC11484 | CPI-169 S-enantiomer | - | >98% | |
EZH2 inhibitor | ||||
| GC12146 | CPI-169 R-enantiomer | 1802175-07-0 | >98% | |
EZH2 inhibitor | ||||
| GC16599 | CPI-169 | 1450655-76-1 | >98.00% | |
EZH2 inhibitor | ||||