FLAP

FLAP (5-lipoxygenase activating protein) is an integral protein within the nuclear membrane and is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes.

Products Related to FLAP(10)

GC11457 MK-0591
CAS: 136668-42-3
Purity: >99.00%
An inhibitor of FLAP
GC12232 BAY-X 1005
CAS: 128253-31-6
Purity: >98.50%
BAY-X 1005 (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor.
GC12277 MK 886
CAS: 118414-82-7
Purity: >99.50%
MK 886 is a 5-lipoxygenase-activating protein (FLAP) inhibitor and PPARα antagonist (IC 50 =30nM).
GC15506 GSK2190915 sodium salt
CAS: 1196070-26-4
Purity: >99.00%
GSK2190915 sodium salt (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
GC31689 Fiboflapon (GSK2190915)
CAS: 936350-00-4
Purity: >98.50%
Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
GC31839 AM 103
CAS: 1147872-22-7
Purity: >98%
AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
GC37059 Quiflapon sodium
CAS: 147030-01-1
Purity: >98.50%
Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.
GC62422 Atuliflapon
CAS: 2041075-86-7
Purity: >98.00%
Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5?Lipoxygenase activating protein), with an IC50 of 2 nM.
GC69101 FEN1-IN-2
CAS: 824983-94-0
Purity: >98%
FEN1-IN-2 (compound 20) is an inhibitor of flap endonuclease 1 (FEN1), with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
GC73487 FEN1-IN-5
CAS: 824983-93-9
Purity: >99.00%
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC11457	MK-0591	136668-42-3	>99.00%
GC11457	An inhibitor of FLAP
GC12232	BAY-X 1005	128253-31-6	>98.50%
GC12232	BAY-X 1005 (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor.
GC12277	MK 886	118414-82-7	>99.50%
GC12277	MK 886 is a 5-lipoxygenase-activating protein (FLAP) inhibitor and PPARα antagonist (IC 50 =30nM).
GC15506	GSK2190915 sodium salt	1196070-26-4	>99.00%
GC15506	GSK2190915 sodium salt (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
GC31689	Fiboflapon (GSK2190915)	936350-00-4	>98.50%
GC31689	Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
GC31839	AM 103	1147872-22-7	>98%
GC31839	AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
GC37059	Quiflapon sodium	147030-01-1	>98.50%
GC37059	Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.
GC62422	Atuliflapon	2041075-86-7	>98.00%
GC62422	Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5?Lipoxygenase activating protein), with an IC50 of 2 nM.
GC69101	FEN1-IN-2	824983-94-0	>98%
GC69101	FEN1-IN-2 (compound 20) is an inhibitor of flap endonuclease 1 (FEN1), with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
GC73487	FEN1-IN-5	824983-93-9	>99.00%
GC73487	FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair.