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AMP PNP

Catalog No.GC50334

AMP PNP (tétralithium adénylyl-imidodiphosphate) est un analogue non hydrolysable de l'ATP et inhibe les canaux KATP.

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AMP PNP Chemical Structure

Cas No.: 72957-42-7

Taille Prix Stock Qté
1mg
54,00 $US
En stock
5mg
161,00 $US
En stock
10mg
284,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.

References:
[1].Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134 .
[2].Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768.
[3].Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231 PMID:7805625.

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