Fenoxycarb (Synonyms: ABG 6215, Ro 13-5223) |
Catalog No.GC47338
One-Click Copy Product Info
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A non-neurotoxic carbamate insecticide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 72490-01-8
Sample solution is provided at 25 µL, 10mM.
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Fenoxycarb is a non-neurotoxic carbamate insecticide that acts as an insect growth regulator via juvenile hormone-like activity.1 It inhibits terminal development of first instar and newly transformed second instar nymphs of Florida red scale (C. aonidum) when used at a concentration of 0.0125% AI.2 Fenoxycarb (5 and 10 mg AI/colony) reduces the colony size index of laboratory colonies of red imported fire ants (S. invicta) by 93.6 to 95.9% at 8 weeks post-treatment.3 It is toxic to D. magna (LC50 = 0.5 mg a.s./L) and fish including O. mykiss, L. macrochirus, C. carpio, I. punctatus, and C. variegatus (LC50s = 0.66-1.5 mg a.s./L), but is not toxic to rats (LD50 = >10,000 mg/kg).4 Fenoxycarb is also an antagonist of α4β40-, α4β2-, α3β4-, and α3β2-containing rat nicotinic acetylcholine receptors (nAChRs; IC50s = 3, 2.4, 1.8, and 7.6 μM, respectively) but not rat brain acetylcholinesterase (AChE; IC50 = >1,000 μM).5
1.Grenier, S., and Grenier, A.M.Fenoxycarb, a fairly new insect growth regulator: A review of its effects on insectsAnn. Appl. Biol.122(2)369-403(1993) 2.Peleg, B.A.Effect of a new insect growth regulator, RO 13-5223, on hymenopterous parasites of scale insectsPhytoparasitica10(1)27-31(1983) 3.Banks, W.A., Williams, D.F., and Lofgren, C.S.Effectiveness of fenoxycarb for control of red imported fire ants (Hymenoptera: Formicidae)J. Econ. Entomol.81(1)83-87(1988) 4.Authority, E.F.S.Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarbEFSA J.8(12)1779(2010) 5.Smulders, C.J., Bueters, T.J., Van Kleef, R.G., et al.Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesteraseToxicol. Appl. Pharmacol.193(2)139-146(2003)
| Cas No. | 72490-01-8 | SDF | |
| Synonymes | ABG 6215, Ro 13-5223 | ||
| Canonical SMILES | O=C(OCC)NCCOC(C=C1)=CC=C1OC2=CC=CC=C2 | ||
| Formula | C17H19NO4 | M.Wt | 301.3 |
| Solubility | DMSO : 8.33 mg/mL (27.64 mM; ultrasonic and warming and heat to 60°C) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.319 mL | 16.5948 mL | 33.1895 mL |
| 5 mM | 663.8 μL | 3.319 mL | 6.6379 mL |
| 10 mM | 331.9 μL | 1.6595 mL | 3.319 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)