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c-Fms-IN-8

Catalog No.GC35665

c-Fms-IN-8 (composé 4a) est un inhibiteur de type II du récepteur du facteur 1 de stimulation des colonies (CSF-1R, c-FMS), avec une IC50 de 9,1 nM.

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c-Fms-IN-8 Chemical Structure

Cas No.: 1255303-58-2

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Description Chemical Properties Product Documents Related Products

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1]. IC50: 9.1 nM (CSF-1R)[1].

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

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