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CPUY074020

Catalog No.GC35742

CPUY074020 est un inhibiteur biodisponible puissant et oral de l'histone méthyltransférase G9a, avec une IC50 de 2,18 μM. CPUY074020 possède une activité anti-proliférative.

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CPUY074020 Chemical Structure

Cas No.: 902279-44-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CPUY074020 is a potent G9a inhibitor with an IC50 of 2.18 μM, and possesses anti-proliferative activity [1]. IC50: 2.18 μM (G9a)[1]

[1]. Chen WL, et al. Discovery, design and synthesis of 6H-anthra[1,9-cd]isoxazol-6-one scaffold as G9a inhibitor through a combination of shape-based virtual screening and structure-based molecular. Bioorg Med Chem. 2016 Nov 15;24(22):6102-6108.

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Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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