Glycycoumarin |
| Catalog No.GC36163 |
La glycycoumarine est un puissant antispasmodique. La glycycoumarine est une coumarine bioactive majeure de la réglisse et présente une activité antispasmodique. La glycycoumarine a également un effet hépatoprotecteur. La glycycoumarine peut être utilisée pour la recherche des douleurs abdominales et des maladies du foie.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 94805-82-0
Sample solution is provided at 25 µL, 10mM.
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Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].
[1]. Zhang E, et al. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Sci Rep. 2016 Nov 30;6:38138. [2]. Song X, et al. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase. Oncotarget. 2016 Oct 4;7(40):65732-65743.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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