Galgravin (Synonyms: (±)-Galgravin) |
| Catalog No.GC38610 |
La galgravine est un composé actif de Nectandra megapotamica, avec une activité anti-inflammatoire. La galgravine présente une activité cytotoxique in vitro et induit l'apoptose dans les cellules leucémiques.
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Cas No.: 528-63-2
Sample solution is provided at 25 µL, 10mM.
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Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].
Galgravin has cytotoxic activity against human leukemia tumor cells with an IC50 of 16.5 µg/mL[2].
[1]. da Silva Filho AA, et al. Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. J Pharm Pharmacol. 2004 Sep;56(9):1179-84. [2]. Ponci V, et al. Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells. Molecules. 2015 Jul 15;20(7):12757-68.
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