Ilimaquinone |
| Catalog No.GC18545 |
L'ilimaquinone, un métabolite de l'éponge marine, présente une activité anticancéreuse via la voie médiée par GADD153.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71678-03-0
Sample solution is provided at 25 µL, 10mM.
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Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. In mammalian cells, 25 uM ilimaquinone reversibly induces vesiculation of Golgi membranes, blocking the secretory pathway. It inhibits the conversion of S-adenosylhomocysteine (SAH) to homocysteine by SAH hydrolase (IC50 = 40 uM). Ilimaquinone also inhibits DNA polymerase β and dual specificity phosphatase Cdc25B (IC50 = 45.2 and 92 uM, respectively) and, at 10 uM, activates gene expression through hypoxia-inducible factor-1.
Review for Ilimaquinone
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
Review for Ilimaquinone
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