Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC49372Kaempferol 7-neohesperidosideCAS: 17353-03-6Purity: >95.00%
A flavonoid glycoside with antioxidant and anticancer activities
- GC49420Gallic Acid-d2CAS: 294660-92-7Purity: >99.00%
An internal standard for the quantification of gallic acid
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0Purity: >95.00%
A peptide agonist of PAR2
- GC49426Taurine-d4CAS: 342611-14-7Purity: >99.00%
An internal standard for the quantification of taurine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8Purity: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52027IsolariciresinolCAS: 548-29-8Purity: >98.00%
L'isolariciresinol ((+)-Cyclolariciresinol) peut être utilisé pour la recherche des rhumatites.
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8Purity: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52081ChamazuleneCAS: 529-05-5Purity: >98.00%
Le chamazulène, un composé naturel, est un inhibiteur de type antioxydant de la formation des leucotriènes B4.
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin est un inhibiteur efficace et métaboliquement stable du système xc- ainsi qu'un inducteur de la ferroptose.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49372 | Kaempferol 7-neohesperidoside | 17353-03-6 | >95.00% | |
A flavonoid glycoside with antioxidant and anticancer activities | ||||
| GC49420 | Gallic Acid-d2 | 294660-92-7 | >99.00% | |
An internal standard for the quantification of gallic acid | ||||
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
L6H21, un dérivé de Chalcone, est un inhibiteur de la différenciation myéloÏde 2 (MD-2) actif par voie orale, puissant et spécifique. | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
La reutérine est un agent antimicrobien À large spectre actif contre les bactéries Gram positives et Gram négatives, ainsi que les levures, les moisissures et les protozoaires. | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
L'isolariciresinol ((+)-Cyclolariciresinol) peut être utilisé pour la recherche des rhumatites. | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
Le chamazulène, un composé naturel, est un inhibiteur de type antioxydant de la formation des leucotriènes B4. | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
Le Cu-ATSP, un puissant inhibiteur de la mort des cellules ferroptotiques, est presque 20 fois plus puissant que le CuATSM. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin est un inhibiteur efficace et métaboliquement stable du système xc- ainsi qu'un inducteur de la ferroptose. | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||