Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC48414Tribuloside (hydrate)Purity: >95.00%
A flavonoid with antibacterial and antioxidant activities
- GC48507Kaempferol 3-O-galactosideCAS: 23627-87-4Purity: >98.00%
Le kaempférol 3-O-galactoside (Trifolin) est un dérivé de flavonoÏde, qui est isolé de la partie aérienne de Consolida oliveriana.
- GC48703Palmarumycin C3CAS: 159934-11-9Purity: >95.00%
La palmarumycine C3 est un composé spirobisnaphtalène isolé À partir de cultures du champignon endophyte Berkleasmium sp.
- GC48764Sydowinin BCAS: 58450-00-3Purity: >95.00%
A xanthone polyketide with immunosuppressant activity
- GC48889Methazolamide-d6CAS: 1795142-30-1Purity: >99.00%
An internal standard for the quantification of methazolamide
- GC48973Sekikaic AcidCAS: 607-11-4Purity: >95.00%
A lichen metabolite with diverse biological activities
- GC49015Phenethyl isothiocyanateCAS: 2257-09-2Purity: >99.00%
An isothiocyanate with anticancer activity
- GC49062Tiopronin-d3CAS: 1189700-74-0Purity: >99.00%
La tiopronine-d3 est la tiopronine marquée au deutérium.
- GC49120Prosaptide TX14(A) (trifluoroacetate salt)Purity: >98.00%
A peptide fragment of prosaposin and GPR37L1 and GPR37 agonist
- GC492335-Feruloylquinic AcidCAS: 40242-06-6Purity: >98.00%
L'acide 5-féruloylquinique (5-FQA) possède des effets antioxydants et des activités inhibitrices de la tyrosinase.
- GC49271Glufosinate-d3 (hydrochloride)CAS: 1323254-05-2Purity: >99.00%
An internal standard for the quantification of glufosinate
- GC49290Indoxyl Sulfate-d5 (potassium salt)CAS: 1644451-34-2Purity: >99.00%
An internal standard for the quantification of indoxyl sulfate
- GC493395(6)-Carboxy-2′,7′-dichlorofluorescein diacetateCAS: 127770-45-0Purity: >90.00%
Le diacétate de 5(6)-carboxy-′,7′-dichlorofluorescéine est un indicateur fluorescent à pénétration cellulaire.
- GC49344Fisetin-d5CAS: 2909407-29-8Purity: >99.00%
An internal standard for the quantification of fisetin
- GC493643-HydroxycoumarinCAS: 939-19-5Purity: >97.00%
La 3-hydroxycoumarine est un inhibiteur puissant et redox de la 15-LOX-1 humaine.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC48401 | Risuteganib (trifluoroacetate salt) | - | >95.00% | |
An anti-integrin peptide | ||||
| GC48414 | Tribuloside (hydrate) | - | >95.00% | |
A flavonoid with antibacterial and antioxidant activities | ||||
| GC48507 | Kaempferol 3-O-galactoside | 23627-87-4 | >98.00% | |
Le kaempférol 3-O-galactoside (Trifolin) est un dérivé de flavonoÏde, qui est isolé de la partie aérienne de Consolida oliveriana. | ||||
| GC48703 | Palmarumycin C3 | 159934-11-9 | >95.00% | |
La palmarumycine C3 est un composé spirobisnaphtalène isolé À partir de cultures du champignon endophyte Berkleasmium sp. | ||||
| GC48764 | Sydowinin B | 58450-00-3 | >95.00% | |
A xanthone polyketide with immunosuppressant activity | ||||
| GC48771 | Avobenzone-13C-d3 | 2933758-47-3 | >99.00% | |
| GC48889 | Methazolamide-d6 | 1795142-30-1 | >99.00% | |
An internal standard for the quantification of methazolamide | ||||
| GC48973 | Sekikaic Acid | 607-11-4 | >95.00% | |
A lichen metabolite with diverse biological activities | ||||
| GC49015 | Phenethyl isothiocyanate | 2257-09-2 | >99.00% | |
An isothiocyanate with anticancer activity | ||||
| GC49062 | Tiopronin-d3 | 1189700-74-0 | >99.00% | |
La tiopronine-d3 est la tiopronine marquée au deutérium. | ||||
| GC49081 | DL-o-Tyrosine | 2370-61-8 | >95.00% | |
A phenylalanine hydroxylation product | ||||
| GC49106 | Gentisein | 529-49-7 | >95.00% | |
La gentiseine (NSC 329491), le principal métabolite de la mangiférine, présente l'inhibition de l'absorption de la sérotonine la plus puissante avec une valeur IC50 de 4,7 μM. | ||||
| GC49120 | Prosaptide TX14(A) (trifluoroacetate salt) | - | >98.00% | |
A peptide fragment of prosaposin and GPR37L1 and GPR37 agonist | ||||
| GC49177 | Loliolide | 5989-02-6 | >98.00% | |
Loliolide est une lactone monoterpénique aux activités biologiques variées. | ||||
| GC49222 | Mitoquinol-d15 | - | >99.00% | |
An internal standard for the quantification of mitoquinol | ||||
| GC49233 | 5-Feruloylquinic Acid | 40242-06-6 | >98.00% | |
L'acide 5-féruloylquinique (5-FQA) possède des effets antioxydants et des activités inhibitrices de la tyrosinase. | ||||
| GC49259 | Antagonist G (trifluoroacetate salt) | - | >98.00% | |
A neuropeptide antagonist | ||||
| GC49271 | Glufosinate-d3 (hydrochloride) | 1323254-05-2 | >99.00% | |
An internal standard for the quantification of glufosinate | ||||
| GC49290 | Indoxyl Sulfate-d5 (potassium salt) | 1644451-34-2 | >99.00% | |
An internal standard for the quantification of indoxyl sulfate | ||||
| GC49329 | Turkesterone (hydrate) | - | >95.00% | |
A phytoecdysteroid with diverse biological activities | ||||
| GC49336 | AMK (hydrochloride) | 1215711-91-3 | >95.00% | |
An active metabolite of melatonin | ||||
| GC49339 | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate | 127770-45-0 | >90.00% | |
Le diacétate de 5(6)-carboxy-′,7′-dichlorofluorescéine est un indicateur fluorescent à pénétration cellulaire. | ||||
| GC49344 | Fisetin-d5 | 2909407-29-8 | >99.00% | |
An internal standard for the quantification of fisetin | ||||
| GC49364 | 3-Hydroxycoumarin | 939-19-5 | >97.00% | |
La 3-hydroxycoumarine est un inhibiteur puissant et redox de la 15-LOX-1 humaine. | ||||
