Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)CAS: 136461-80-8Purity: >95.00%
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)Purity: >95.00%
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
- GC44544Palmitoleic Acid (sodium salt)CAS: 6610-24-8Purity: >95.00%
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
- GC44598Peptide YY (human) (trifluoroacetate salt)Purity: >95.00%
Peptide YY (human) (trifluoroacetate salt) est une hormone peptidique sécrétée par les cellules L intestinales.
- GC44645Pioglitazone (potassium salt)CAS: 1266523-09-4Purity: >98.00%
La pioglitazone (U 72107) potassique est un PPARγ actif et sélectif par voie orale ; (récepteur activé par les proliférateurs de peroxysomes) avec une liaison de haute affinité au PPARγ ; domaine de liaison au ligand avec EC50 de 0,93 μ M et 0,99 μ M pour PPARγ humain et murin, respectivement.
- GC44660PlatensimycinCAS: 835876-32-9Purity: >95.00%
Platensimycin (PTM) is an antibiotic produced by S.
- GC44775PTP1B InhibitorCAS: 765317-72-4Purity: >98.00%
L'inhibiteur de PTP1B est un inhibiteur allostérique non compétitif de la protéine tyrosine phosphatase PTP1B, avec une IC50 de 8 μ ;M.
- GC44811Remogliflozin etabonateCAS: 442201-24-3Purity: >99.00%
L'étabonate de rémogliflozine (GSK189075) est un inhibiteur du cotransporteur sodium glucose (SGLT2) actif par voie orale, sélectif et de faible affinité avec des valeurs Ki de 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM pour hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectivement.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM).
- GC44895Sitagliptin N-Sulfate (sodium salt)CAS: 2470126-25-9Purity: >95.00%
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44914Somatostatin-14 (acetate)CAS: 54472-66-1Purity: >98.00%
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.
- GC45139Vapreotide (trifluoroacetate salt)Purity: >95.00%
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay).
- GC45144Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)CAS: 565453-41-0Purity: >98.00%
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45252(-)-Sitagliptin Carbamoyl GlucuronideCAS: 940002-59-5Purity: >90.00%
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44518 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | 136461-80-8 | >95.00% | |
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. | ||||
| GC44524 | Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) | - | >95.00% | |
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. | ||||
| GC44529 | P053 | 2748196-63-4 | >97.00% | |
P053 est un inhibiteur puissant, non compétitif et sélectif de la céramide synthase 1 (CerS1) avec une IC50 de 0,5μM. | ||||
| GC44544 | Palmitoleic Acid (sodium salt) | 6610-24-8 | >95.00% | |
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | ||||
| GC44598 | Peptide YY (human) (trifluoroacetate salt) | - | >95.00% | |
Peptide YY (human) (trifluoroacetate salt) est une hormone peptidique sécrétée par les cellules L intestinales. | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
La pioglitazone (U 72107) potassique est un PPARγ actif et sélectif par voie orale ; (récepteur activé par les proliférateurs de peroxysomes) avec une liaison de haute affinité au PPARγ ; domaine de liaison au ligand avec EC50 de 0,93 μ M et 0,99 μ M pour PPARγ humain et murin, respectivement. | ||||
| GC44660 | Platensimycin | 835876-32-9 | >95.00% | |
Platensimycin (PTM) is an antibiotic produced by S. | ||||
| GC44775 | PTP1B Inhibitor | 765317-72-4 | >98.00% | |
L'inhibiteur de PTP1B est un inhibiteur allostérique non compétitif de la protéine tyrosine phosphatase PTP1B, avec une IC50 de 8 μ ;M. | ||||
| GC44811 | Remogliflozin etabonate | 442201-24-3 | >99.00% | |
L'étabonate de rémogliflozine (GSK189075) est un inhibiteur du cotransporteur sodium glucose (SGLT2) actif par voie orale, sélectif et de faible affinité avec des valeurs Ki de 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM pour hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectivement. | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM). | ||||
| GC44895 | Sitagliptin N-Sulfate (sodium salt) | 2470126-25-9 | >95.00% | |
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC44914 | Somatostatin-14 (acetate) | 54472-66-1 | >98.00% | |
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. | ||||
| GC44954 | Stevioside (hydrate) | - | >95.00% | |
Stevioside is a natural non-caloric sweetener. | ||||
| GC45139 | Vapreotide (trifluoroacetate salt) | - | >95.00% | |
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay). | ||||
| GC45144 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | 565453-41-0 | >98.00% | |
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. | ||||
| GC45164 | WWL229 | 1338575-28-2 | >98.00% | |
WWL229 est un inhibiteur sélectif de la carboxylestérase 3 (Ces3) avec une IC50 de 1,94 μM. | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45252 | (-)-Sitagliptin Carbamoyl Glucuronide | 940002-59-5 | >90.00% | |
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC45277 | (±)-Camphene | 79-92-5 | >99.50% | |
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| GC45315 | 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol | 2738376-70-8 | >99.00% | |
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| GC45320 | 1-Stearoyl-3-Oleoyl-rac-glycerol | 18266-27-8 | >98.00% | |
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| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
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| GC45490 | Kisspeptin-54 (human) (trifluoroacetate salt) | - | >95.00% | |
| ||||
| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
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