Obesity, Appetite Control & Diabetes

Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Targets for Obesity, Appetite Control & Diabetes
Products for Obesity, Appetite Control & Diabetes
- Cat.No. Nom du produit Informations
-
GC19941
DL-Leucic Acid
-
GC49008
α-Muricholic Acid-d4
ω-MCA-d4
An internal standard for the quantification of α-muricholic acid -
GC90496
β-Cortolone
Un métabolite du cortisol
-
GC40105
βARK1 Inhibitor
βl'inhibiteur d'ARK1 (5-[2-(5-nitro-2-furyl)vinyl]-2-furoate de méthyle) est un inhibiteur de GRK2 (β-ARK1).
-
GC46314
(±)-β-Hydroxybutyrate-d4 (sodium salt)
βHydroxybutanoic Acidd4
An internal standard for the quantification of (±)βhydroxybutyrate -
GC45277
(±)-Camphene
DL-Camphene, NSC 4165
-
GC46308
(±)-Sitagliptin-d4 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC45618
(±)-trans-GK563
GK563
A GVIA iPLA2 inhibitor -
GC40271
(±)5(6)-DiHET MaxSpec® Standard
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC40218
(-)-Epigallocatechin Gallate-d3/d4
EGCG-d3/d4
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. -
GC45252
(-)-Sitagliptin Carbamoyl Glucuronide
(R)-Sitagliptin Carbamoyl Glucuronide
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. -
GC41699
(Des-octanoyl)-Ghrelin (human) (trifluoroacetate salt)
Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).
-
GC49066
(R)-Hydroxychloroquine (sulfate)
(R)-HCQ
An isomer of hydroxychloroquine -
GC49067
(S)-Hydroxychloroquine (sulfate)
(S)-HCQ
An isomer of hydroxychloroquine -
GC20027
(±)5(6)-DiHET MaxSpec® Standard
(±)5,6-DiHETrE
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC46365
1,1'-(Azodicarbonyl)dipiperidine
ADDP, NSC 356027
A Mitsunobu reagent -
GC41777
1,2,3-Tripalmitoleoyl-rac-glycerol
Glyceryl Tripalmitoleate, TG(16:1/16:1/16:1), Tripalmitolein
1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions. -
GC45747
1,2,3-Tripalmitoyl-d31-rac-glycerol
Glycerol Trihexadecanoate-d31, Glycerol Tripalmitate-d31, Glyceryl Tripalmitate-d31, Trihexadecanoyl Glycerol-d31, Tripalmitin-d31, Tripalmitoylglycerol-d31
An internal standard for the quantification of 1,2,3-tripalmitoyl glycerol -
GC41794
1,2-Diheptanoyl-sn-glycero-3-PC
DHPC-C7, di-C7-PC
1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. -
GC46477
1-Amino-1-deoxy-D-fructose (hydrochloride)
D-Fructosamine, D-Isoglucosamine
An amino monosaccharide -
GC42035
1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol
1-Palmitin-2-Stearin-3-Olein, TG(16:0/18:0/18:1)
1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. -
GC45315
1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol
Glycerol Tripalmitate-d9, TG(16:0-d9/16:0/16:0), Tripalmitin-d9, 1,2,3-Tripalmitoyl-sn-glycerol-d9, Tripalmitoylglycerol-d9
-
GC46052
1-Pentadecanoyl-rac-glycerol
MG(15:0/0:0/0:0), 1-Monopentadecanoin
A monoacylglycerol -
GC45320
1-Stearoyl-3-Oleoyl-rac-glycerol
DG(18:0/0:0/18:1), 1-Stearin-3-Olein
-
GC90363
10(11)-Cl-BBQ
Un mélange qui agit comme un agoniste de l'AhR.
-
GC46400
10(11)-Cl-BBQ Mixture
A mixture that acts as an AhR agonist
-
GC40317
10(R)-PAHSA
10(R)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC40318
10(S)-PAHSA
10(S)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC41869
10-OAHSA
10-OAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC52071
10-oxo-12(Z)-Octadecenoic Acid
10-keto-12Z-Octadecenoic Acid, 10-oxo-12-cis-Octadecenoic Acid
A metabolite of linoleic acid and an activator of TRPV1 -
GC52398
10-oxo-12(Z)-Octadecenoic Acid ethyl ester
10-keto-12Z-Octadecenoic Acid ethyl ester, 10-oxo-12-cis-Octadecenoic Acid ethyl ester
An ester form of 10-oxo-12(Z)-octadecenoic acid -
GC52428
10-oxo-12(Z)-Octadecenoic Acid-d5
10-keto-12Z-Octadecenoic Acid-d5, 10-oxo-12-cis-Octadecenoic Acid-d5
An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid -
GC41871
10-POHSA
10-POHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC41872
10-SAHSA
10-SAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC41873
10-Thiastearic Acid
Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools.
-
GC48710
11-Dehydrocorticosterone
11-DHC, DHCS, Kendall's Compound A, NSC 9702
La 11-déhydrocorticostérone est un corticostéroÏde endogène. -
GC40320
12-PAHSA
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.
-
GC46419
12-PAHSA-d31
A neuropeptide with diverse biological activities
-
GC18783
13,14-dihydro-15-keto Prostaglandin E1
11α-Hydroxy-9,15-diketoprostanoic Acid, 15-keto-PGE0, 13,14-dihydro-15-keto PGE1, 15-keto-dihydro-PGE1, 15-keto Prostaglandin E0
13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. -
GC41907
13C C16 Sphingomyelin (d18:1/16:0)
Palmitoyl Sphingomyelin-13C, N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine-13C, SM(d18:1/16:0-13C), Sphingomyelin (d18:1/16:0-13C)
13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. -
GC18635
18-hydroxy-11-deoxy Corticosterone
18-Hydroxydeoxycorticosterone, 18-OH-DOC
18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. -
GC90819
2,3,7,8-Tetrachlorodibenzofuran
Un dibenzofurane polychloré et une dioxine.
-
GC49671
2,3-Oxidosqualene
(3R,S)-Oxidosqualene, Squalene 2,3-oxide
An intermediate in the biosynthesis of sterols -
GC10289
2-NBDG
NBDGlucose
2-NBDG est un analogue fluorescent marqué du 2-désoxy-glucose, utilisé comme traceur pour l'évaluation du métabolisme du glucose cellulaire (Ex/Em : 475/550 nm). -
GC18270
22(S)-hydroxy Cholesterol
22β-hydroxy Cholesterol
A synthetic oxysterol and LXR modulator -
GC48449
28-(Poc-amino)betulin
-
GC46605
3β-Cholic Acid-d4
3β-Epicholic Acid-d4
A neuropeptide with diverse biological activities -
GC49169
3,8’-Biapigenin
I3,II8-Biapigenin, 3,8\-Biapigenin
3,8’-Biapigenine est une biflavone dans Hypericum perforatum L. -
GC46584
3-Aminoisobutyric Acid (sodium salt)
β-Aminoisobutyric Acid, BAIBA
A neuropeptide with diverse biological activities -
GC49850
3-Epideoxycholic Acid
EDCA
A secondary bile acid and an epimer of deoxycholic acid -
GC18403
3-hydroxy Hexanoic Acid
3-hydroxy Caproic Acid
3-hydroxy Hexanoic acid is a hydroxylated fatty acid that has been found in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. -
GC42291
3-Hydroxyisobutyrate (sodium salt)
3-HIB
3-Hydroxyisobutyrate (3-HIB) is an intermediate in the metabolism of the branched-chain amino acid valine that is secreted by skeletal muscle.
-
GC42411
4-hydroxy Nonenal Alkyne
Click Tag 4HNE Alkyne
4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.
-
GC42434
4-methyl-2-Oxovalerate (sodium salt)
2-Ketoisocaproate, α-Ketoisocaproate, 2-Ketoisocaproic Acid, KIC, 4-MOP, 2-Oxoisocaproic Acid, 4-methyl-2-Oxopentanoate, 4-methyl-2-Oxovalerate, 4-methyl-2-Oxovaleric Acid
4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. -
GC49176
5β-Tetrahydrocortisol
NSC 57431
An endogenous metabolite of cortisol -
GC40379
5(S)-HEPE MaxSpec® Standard
5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA).
-
GC42548
5-hydroxy Saxagliptin (hydrochloride)
5-hydroxy Saxagliptin is a major active metabolite of saxagliptin.
-
GC91922
6,6-Dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
6,6-Dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine est un modulateur allostérique positif du récepteur GLP - 1R du peptide 1 de type Glucagon, PAM.
-
GC18870
6-NBDG
6-NBD-Glucose
Le 6-NBDG est un analogue fluorescent du glucose, il peut être utilisé pour l'imagerie par fluorescence et la surveillance du transport et de l'absorption du glucose. -
GC42620
8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt)
APTS
L'acide 8-aminopyrène-1,3,6-trisulfonique (sel de sodium) est un colorant fluorescent anionique soluble dans l'eau. -
GC92043
9(10)-Nitrooleate
9(10)-Nitrooleic Acid; OA-NO2; 9(10)-nitro-9-trans-Octadecenoic Acid
9(10)-Nitrooleate est un mélange des molécules de signalisation des lipides endogènes du nitroalkène 9-nitrooléate. -
GC40323
9(R)-PAHSA
9(R)-PAHSA is a stereoisomer of 9-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC40324
9(S)-PAHSA
9-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
-
GC46757
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
cis-9,trans-11-Conjugated Linoleic Acid, 9(Z),11(E)-CLA
An isomer of linoleic acid -
GC40325
9-PAHSA
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.
-
GC42655
9-PAHSA 13C4
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.
-
GC46763
9-PAHSA-d31
A neuropeptide with diverse biological activities
-
GC46764
9-PAHSA-d4
A neuropeptide with diverse biological activities
-
GP10060
a-MSH, amide
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-amide, α-MSH, amide
a-MSH, amide (α-Hormone Stimulant de Mélanocytes), se lie au récepteur de la mélanocortine-1 et active la signalisation de l’AMP cyclique (cAMP) via un transporteur protéique G, ce qui permet la synthèse de mélanine. -
GC42674
ABD459
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM).
-
GC92095
Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt)
Ac-dR[CEHdFRWC]-NH2
Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt) est un peptide cyclique et un agoniste du récepteur 4 de mélanocortine (MC4R). -
GC49406
ACT-373898
ACT-373898 est un métabolite acide carboxylique inactif du macitentan.
-
GC90949
Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)
Un agoniste du récepteur P2Y11
-
GC46083
Adenylosuccinic Acid
Aspartyl Adenylate
L'acide adénylosuccinique est un nucléotide purique et un intermédiaire dans le cycle des nucléotides puriques.
-
GC49231
Adenylosuccinic Acid (ammonium salt)
A purine nucleotide and an intermediate in the purine nucleotide cycle
-
GP10076
Agouti-related Protein (AGRP) (25-82), human
H2N-Leu-Ala-Pro-Met-Glu-Gly-Ile-Arg-Arg-Pro-Asp-Gln-Ala-Leu-Leu-Pro-Glu-Leu-Pro-Gly-Leu-Gly-Leu-Arg-Ala-Pro-Leu-Lys-Lys-Thr-Thr-Ala-Glu-Gln-Ala-Glu-Glu-Asp-Leu-Leu-Gln-Glu-Ala-Gln-Ala-Leu-Ala-Glu-Val-Leu-Asp-Leu-Gln-Asp-Arg-Glu-Pro-Arg-OH
-
GC49110
AICA Ribonucleotide
AICA-Ribotide, AICA-Riboside-5'-phosphate, 5-Aminoimidazole-4-Carboxamide Ribonucelotide, NSC 283955, NSC 292227
An AMPK activator -
GC46821
Ajoene
L'ajoène, un composé dérivé de l'ail, est un agent antithrombotique et antifongique.
-
GC40812
all-cis-4,7,10,13,16-Docosapentaenoic Acid
all-cis-4,7,10,13,16-DPA, Osbond Acid
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oils. -
GC40289
all-cis-4,7,10,13,16-Docosapentaenoic Acid methyl ester
all-cis-4,7,10,13,16-DPA methyl ester, all-Z-4,7,10,13,16-DPA methyl ester, Osbond Acid methyl ester
all-cis-4,7,10,13,16-Docosapentaenoic acid (all-cis-4,7,10,13,16-DPA) methyl ester is a more lipid-soluble form of the free acid. -
GC40094
all-trans Retinoic Acid-d5
atRA-d5, RA-d5, Vitamin A Acid-d5
all-trans Retinoic acid-d5 is intended for use as an internal standard for the quantification of all-trans retinoic acid by GC- or LC-MS. -
GC49393
all-trans-13,14-Dihydroretinol
A metabolite of all-trans retinoic acid
-
GC45379
Alloxan (hydrate)
-
GC40024
Altenusin
Alutenusin
L'alténusine montre des activités de piégeage radicalaire DPPH marquées. -
GC42786
Aminoacetone (hydrochloride)
1-Amino-2-propanone
Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. -
GC40636
Amorfrutin A
Amorfrutin 1
Amorfrutin A is an isoprenoid-substituted benzoic acid natural product found in the fruit of A. -
GC42791
Amorfrutin B
Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A.
-
GC41406
AMP-Deoxynojirimycin
AdamantanepentyldNM, AMP-DNJ, AMPdNM, N(5adamantane1ylmethoxypentyl)Deoxynojirimycin
The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS). -
GC42795
Amylin (human) (amidated) (trifluoroacetate salt)
IAPP (human) (amidated), Islet Amyloid Polypeptide (human) (amidated)
Amylin is a peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. -
GC42796
Amylin (human) (trifluoroacetate salt)
IAPP (human), Islet Amyloid Polypeptide (human)
Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. -
GC42797
Amylin (rat, mouse) (trifluoroacetate salt)
IAPP (rat, mouse), Islet Amyloid Polypeptide (rat, mouse)
Amylin is a 37-residue peptide hormone secreted by pancreatic β-cells that reduces food intake, modifies glycogen synthesis, slows gastric emptying, and increases satiety. -
GC42805
AN-7
α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form.
-
GC52128
AOD-9604
-
GC52380
AOD-9604 (acetate)
A synthetic lipolytic peptide
-
GC46892
ATRA-BA Hybrid
A prodrug form of all-trans retinoic acid and butyric acid
-
GC49646
Aurothioglucose (hydrate)
Gold Thioglucose
A TrxR inhibitor -
GC72096
Bamadutide
Bamadutide(sar425899) est un puissant Agoniste des récepteurs du peptide - 1 de type diglycémine / récepteur du glucagon.
-
GC52476
Bax Inhibitor Peptide V5 (trifluoroacetate salt)
BIP V5, VPMLK
A Bax inhibitor -
GC40889
Benzomalvin A
(-)-Benzomalvin A
La benzomalvine A est un puissant antagoniste du récepteur de la neurokinine isolé de Penicillium sp. -
GC20142
Beta-Sitosterol
β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%))
Beta-Sitosterol est un stérol végétal avec les multiples activités biologiques, celles qui comprennent les activités anti-inflammatoire, anti-tumorale, antipyrétique et immunodulatrice.