GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC39611 structure
    GC396113'-Hydroxy Repaglinide
    CAS: 874908-14-2
    Purity: >98%

    Le 3'-hydroxyrépaglinide est l'un des principaux métabolites CYP2C8 du répaglinide.

  • GC39757 structure
    GC39757Etilevodopa hydrochloride
    CAS: 39740-30-2
    Purity: >98.50%

    Le chlorhydrate d'étilevodopa (ester éthylique de L-Dopa), un promédicament ester éthylique de la lévodopa, est rapidement hydrolysé en lévodopa et en éthanol par des estérases non spécifiques dans le tractus gastro-intestinal.

  • GC39841 structure
    GC398413,4-Dehydro Cilostazol
    CAS: 73963-62-9
    Purity: >98.00%

    Le 3,4-déhydro cilostazol (OPC-13015) est un métabolite actif du cilostazol.

  • GC40018 structure
    GC40018Donepezil N-oxide
    CAS: 120013-84-5
    Purity: >98.00%

    Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil.

  • GC40099 structure
    GC40099Leukotriene D4 MaxSpec® Standard
    CAS: 73836-78-9
    Purity: >97.00%

    Leucotriène D4 MaxSpec® ; Standard est un puissant bronchoconstricteur.

  • GC40143 structure
    GC40143Dihydrotetrabenazine
    CAS: 3466-75-9
    Purity: >98.00%

    Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases.

  • GC40144 structure
    GC40144Levofloxacin N-oxide
    CAS: 117678-38-3
    Purity: >95.00%

    Le N-oxyde de lévofloxacine est un métabolite mineur de la lévofloxacine.

  • GC40145 structure
    GC40145(S)-Laudanosine
    CAS: 2688-77-9
    Purity: >98.00%

    (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.

  • GC40190 structure
    GC40190Febuxostat Acyl Glucuronide
    CAS: 1351692-92-6
    Purity: >98.00%

    Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat.

  • GC40191 structure
    GC40191Ibuprofen Carboxylic Acid
    CAS: 15935-54-3
    Purity: >98.00%

    Ibuprofen carboxylic acid is a major metabolite of ibuprofen.

  • GC40286 structure
    GC40286(E,Z)-2-propyl-2-Pentenoic Acid
    CAS: 60218-41-9
    Purity: >98.00%

    (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.

  • GC40298 structure
    GC40298N-acetyl-5-Aminosalicylic Acid
    CAS: 51-59-2
    Purity: >98.00%

    N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine.

  • GC40300 structure
    GC40300Dihydroresveratrol
    CAS: 58436-28-5
    Purity: >98.00%

    Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota.

  • GC40301 structure
    GC40301Tamoxifen N-oxide
    CAS: 75504-34-6
    Purity: >98.00%

    Tamoxifen is a selective estrogen receptor modulator that evokes tissue-dependent effects.

  • GC40480 structure
    GC40480α-Phenyl-α-(2-pyridyl)acetonitrile
    CAS: 5005-36-7
    Purity: >98.00%

    α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion.

  • GC40529 structure
    GC405297-hydroxy Warfarin
    CAS: 17834-03-6
    Purity: >98%

    7-hydroxy Warfarin is a metabolite of (-)-warfarin, which is a more potent vitamin K antagonist than (+)-warfarin.

  • GC40616 structure
    GC40616Des-4-fluorobenzyl Mosapride
    CAS: 152013-26-8
    Purity: >96.00%

    Des-4-fluorobenzyl Mosapride is the primary metabolite of mosapride.

  • GC40627 structure
    GC40627tetranor-Misoprostol
    Purity: >95.00%

    tetranor-Misoprostol is a metabolite of misoprostol.

  • GC40675 structure
    GC406752-deoxy-Artemisinin
    CAS: 72826-63-2
    Purity: >98.00%

    2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.

  • GC40834 structure
    GC40834cis-Entacapone
    CAS: 145195-63-7
    Purity: >98.00%

    cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone.

  • GC40852 structure
    GC40852N-Demethylerythromycin A
    CAS: 992-62-1
    Purity: >95.00%

    N-Demethylerythromycin A is a metabolite of erythromycin.

  • GC40879 structure
    GC408794-hydroxy Solifenacin N-oxide
    CAS: 2747991-39-3
    Purity: >95.00%

    4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .

  • GC40968 structure
    GC4096821-hydroxy Eplerenone
    CAS: 334678-67-0
    Purity: >98.00%

    21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.

  • GC41154 structure
    GC411542-keto-D-Glucose
    CAS: 1854-25-7
    Purity: >95.00%

    2-keto-D-Glucose est un intermédiaire essentiel de la voie de biosynthèse de l'antibiotique cortalcérone, c'est aussi un composé métabolique clé dans la transformation de D-glucose en D-fructose.