Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC41177Lurasidone metabolite 14283CAS: 186204-31-9Purity: >95.00%
Lurasidone metabolite 14283 is an active metabolite of the atypical antipsychotic lurasidone .
- GC41266Pregnanediol-3-GlucuronideCAS: 1852-49-9Purity: >95.00%
Le prégnandiol-3-glucuronide est le principal métabolite terminal de la progestérone, jouant un rôle important dans les processus physiologiques, tels que le cycle menstruel féminin, la grossesse (soutient la gestation), l'embryogenèse et la réponse immunitaire maternelle des humains et d'autres espèces.
- GC41270N-desmethyl ZolmitriptanCAS: 139264-35-0Purity: >95.00%
N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan.
- GC4130017β-hydroxy ExemestaneCAS: 122370-91-6Purity: >98.00%
17β-hydroxy Exemestane is the primary active metabolite of exemestane.
- GC4130916α-hydroxy PrednisoloneCAS: 13951-70-7Purity: >98.00%
16α-hydroxy Prednisolone est un métabolite stéréosélectif de l'épimère 22(R) du budésonide glucocorticoÏde via les enzymes du cytochrome P450 3A (CYP3A).
- GC413125-hydroxy OmeprazoleCAS: 92340-57-3Purity: >98.00%
5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump.
- GC41315(±)-Ketoprofen GlucuronideCAS: 76690-94-3Purity: >95.00%
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
- GC41325Mycophenolic Acid β-D-GlucuronideCAS: 31528-44-6Purity: >98.00%
L'acide mycophénolique β-D-Glucuronide est un métabolite de l'acide mycophénolique immunosuppresseur (MPA). L'acide mycophénolique β-D-Glucuronide présente une activité anti-tumorale et peut être utilisé dans la recherche sur l'adénocarcinome.
- GC41339Pioglitazone KetoneCAS: 146062-45-5Purity: >98.00%
Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone.
- GC41380N-desmethyl RosiglitazoneCAS: 257892-31-2Purity: >98.00%
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone, a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes.
- GC413995α-dihydro LevonorgestrelCAS: 78088-19-4Purity: >95.00%
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel.
- GC414803'-hydroxy LidocaineCAS: 34604-55-2Purity: >98.00%
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.
- GC415653-hydroxy MedetomidineCAS: 128366-50-7Purity: >95.00%
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine.
- GC41661(±)-4-hydroxy Propranolol β-D-GlucuronideCAS: 94731-13-2Purity: >90.00%
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
- GC41671(±)-Equol 4'-sulfate (sodium salt)CAS: 1189685-28-6Purity: >90.00%
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
- GC41694(3S)-hydroxy QuinidineCAS: 53467-23-5Purity: >98.00%
(3S)-hydroxy Quinidine is an active quinidine metabolite.
- GC41722(R,S)-Carvedilol GlucuronideCAS: 114869-83-9Purity: >95.00%
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
- GC41736(S)-Dibutyl 3-Hydroxybutyl PhosphateCAS: 2108602-99-7Purity: >95.00%
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP).
- GC418371,3,7-Trimethyluric AcidCAS: 5415-44-1Purity: >98.00%
L'acide 1,3,7-triméthylurique est le métabolite de la caféine. Le rapport métabolique de l'acide 1,3,7-triméthylurique À la caféine peut être évalué en tant que biomarqueur pour décrire la variabilité de l'activité du CYP3A dans une cohorte.
- GC4193715-keto-17-phenyl trinor Prostaglandin F2α ethyl amideCAS: 1163135-96-3Purity: >98.00%
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
- GC421892-oxo ClopidogrelCAS: 109904-27-0Purity: >98.00%
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
- GC421983-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)CAS: 1346603-21-1Purity: >98.00%
An inactive metabolite of baclofen
- GC422743-hydroxy DarifenacinCAS: 206048-82-0Purity: >95.00%
3-hydroxy Darifenacin is a metabolite of darifenacin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC41177 | Lurasidone metabolite 14283 | 186204-31-9 | >95.00% | |
Lurasidone metabolite 14283 is an active metabolite of the atypical antipsychotic lurasidone . | ||||
| GC41249 | p,p'-DDD | 72-54-8 | >98.00% | |
Le p,p'-DDD est un métabolite majeur du p,p'-DDT. | ||||
| GC41266 | Pregnanediol-3-Glucuronide | 1852-49-9 | >95.00% | |
Le prégnandiol-3-glucuronide est le principal métabolite terminal de la progestérone, jouant un rôle important dans les processus physiologiques, tels que le cycle menstruel féminin, la grossesse (soutient la gestation), l'embryogenèse et la réponse immunitaire maternelle des humains et d'autres espèces. | ||||
| GC41270 | N-desmethyl Zolmitriptan | 139264-35-0 | >95.00% | |
N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan. | ||||
| GC41300 | 17β-hydroxy Exemestane | 122370-91-6 | >98.00% | |
17β-hydroxy Exemestane is the primary active metabolite of exemestane. | ||||
| GC41309 | 16α-hydroxy Prednisolone | 13951-70-7 | >98.00% | |
16α-hydroxy Prednisolone est un métabolite stéréosélectif de l'épimère 22(R) du budésonide glucocorticoÏde via les enzymes du cytochrome P450 3A (CYP3A). | ||||
| GC41312 | 5-hydroxy Omeprazole | 92340-57-3 | >98.00% | |
5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump. | ||||
| GC41315 | (±)-Ketoprofen Glucuronide | 76690-94-3 | >95.00% | |
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen. | ||||
| GC41325 | Mycophenolic Acid β-D-Glucuronide | 31528-44-6 | >98.00% | |
L'acide mycophénolique β-D-Glucuronide est un métabolite de l'acide mycophénolique immunosuppresseur (MPA). L'acide mycophénolique β-D-Glucuronide présente une activité anti-tumorale et peut être utilisé dans la recherche sur l'adénocarcinome. | ||||
| GC41339 | Pioglitazone Ketone | 146062-45-5 | >98.00% | |
Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone. | ||||
| GC41380 | N-desmethyl Rosiglitazone | 257892-31-2 | >98.00% | |
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone, a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. | ||||
| GC41399 | 5α-dihydro Levonorgestrel | 78088-19-4 | >95.00% | |
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel. | ||||
| GC41480 | 3'-hydroxy Lidocaine | 34604-55-2 | >98.00% | |
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. | ||||
| GC41565 | 3-hydroxy Medetomidine | 128366-50-7 | >95.00% | |
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine. | ||||
| GC41661 | (±)-4-hydroxy Propranolol β-D-Glucuronide | 94731-13-2 | >90.00% | |
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol. | ||||
| GC41671 | (±)-Equol 4'-sulfate (sodium salt) | 1189685-28-6 | >90.00% | |
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol. | ||||
| GC41694 | (3S)-hydroxy Quinidine | 53467-23-5 | >98.00% | |
(3S)-hydroxy Quinidine is an active quinidine metabolite. | ||||
| GC41722 | (R,S)-Carvedilol Glucuronide | 114869-83-9 | >95.00% | |
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. | ||||
| GC41736 | (S)-Dibutyl 3-Hydroxybutyl Phosphate | 2108602-99-7 | >95.00% | |
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). | ||||
| GC41837 | 1,3,7-Trimethyluric Acid | 5415-44-1 | >98.00% | |
L'acide 1,3,7-triméthylurique est le métabolite de la caféine. Le rapport métabolique de l'acide 1,3,7-triméthylurique À la caféine peut être évalué en tant que biomarqueur pour décrire la variabilité de l'activité du CYP3A dans une cohorte. | ||||
| GC41937 | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | 1163135-96-3 | >98.00% | |
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. | ||||
| GC42189 | 2-oxo Clopidogrel | 109904-27-0 | >98.00% | |
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel. | ||||
| GC42198 | 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) | 1346603-21-1 | >98.00% | |
An inactive metabolite of baclofen | ||||
| GC42274 | 3-hydroxy Darifenacin | 206048-82-0 | >95.00% | |
3-hydroxy Darifenacin is a metabolite of darifenacin. | ||||