GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC43493 structure
    GC43493DL-Sulforaphane N-acetyl-L-cysteine
    CAS: 334829-66-2
    Purity: >98.00%

    Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.

  • GC43565 structure
    GC43565Doxorubicinol (hydrochloride)
    CAS: 63950-05-0
    Purity: >90.00%

    Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.

  • GC43646 structure
    GC43646Ezetimibe Hydroxy Glucuronide
    CAS: 536709-33-8
    Purity: >95.00%

    Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe .

  • GC43675 structure
    GC43675Florfenicol amine (hydrochloride)
    CAS: 108656-33-3
    Purity: >95.00%

    Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.

  • GC43697 structure
    GC43697Formoterol O-β-D-Glucuronide
    CAS: 615551-59-2
    Purity: >95.00%

    Formoterol O-β-D-glucuronide is a metabolite of formoterol .

  • GC43743 structure
    GC43743Gemfibrozil 1-O-β-Glucuronide
    CAS: 91683-38-4
    Purity: >99.5%

    Gemfibrozil 1-O-β-Glucuronide, un métabolite du Gemfibrozil, est un inhibiteur puissant et compétitif de l'isoforme CYP2C8 du P450 (CYP) avec une IC50 de 4,07 μM.

  • GC43878 structure
    GC43878Hydroxy Dimetridazole
    CAS: 936-05-0
    Purity: >98.50%

    Hydroxy Dimetridazole (Hydroxy dimetridazole) est un métabolite hydroxy du Dimetridazole.

  • GC43879 structure
    GC43879Hydroxy Ebastine
    CAS: 210686-41-2
    Purity: >87.00%

    Hydroxy Ebastine is an ebastine metabolite.

  • GC43881 structure
    GC43881Hydroxy Varenicline
    CAS: 357424-21-6
    Purity: >95.00%

    A metabolite of varenicline

  • GC43895 structure
    GC43895Iloperidone metabolite P88
    CAS: 133454-55-4
    Purity: >99.50%

    Le métabolite P88 de l'ilopéridone (P88 ; Hydroxy Iloperidone) est un métabolite de l'ilopéridone, qui est un antipsychotique atypique.

  • GC43896 structure
    GC43896Iloperidone metabolite P95
    CAS: 475110-48-6
    Purity: >98.00%

    Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone.

  • GC44033 structure
    GC44033Lansoprazole sulfone
    CAS: 131926-99-3
    Purity: >98.00%

    Lansoprazole sulfone is a phase I metabolite of lansoprazole.

  • GC44246 structure
    GC44246Moxifloxacin N-Sulfate (sodium salt)
    Purity: >95.00%

    Moxifloxacin N-sulfate is a metabolite of moxifloxacin.

  • GC44294 structure
    GC44294N-acetyl Dapsone
    CAS: 565-20-8
    Purity: >95.00%

    N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders.

  • GC44299 structure
    GC44299N-Acetyl-4-benzoquinone imine
    CAS: 50700-49-7
    Purity: >90.00%

    La N-acétyl-4-benzoquinone imine est le métabolite toxique de l'acétaminophène.

  • GC44304 structure
    GC44304N-Acetyl-S-allyl-L-cysteine
    CAS: 23127-41-5
    Purity: >98.00%

    L-Deoxyalliin, also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.

  • GC44345 structure
    GC44345N-Desethyl Vardenafil
    CAS: 448184-46-1
    Purity: >98.00%

    N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.

  • GC44348 structure
    GC44348N-desmethyl Bendamustine
    CAS: 41515-13-3
    Purity: >95.00%

    N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine.

  • GC44349 structure
    GC44349N-desmethyl Levofloxacin
    CAS: 117707-40-1
    Purity: >98.00%

    La N-desméthyl lévofloxacine est un métabolite de la lévofloxacine.

  • GC44350 structure
    GC44350N-Desmethyl Sildenafil
    CAS: 139755-82-1
    Purity: >98.00%

    Le N-Desmethyl Sildenafil (Desmethylsildenafil) est un métabolite majeur du Sildenafil.

  • GC44351 structure
    GC44351N-Desmethyl Sildenafil (citrate)
    Purity: >98.00%

    N-Desmethyl sildenafil is a major metabolite of sildenafil.

  • GC44358 structure
    GC44358Nebivolol O-β-D-Glucuronide
    Purity: >95.00%

    Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.

  • GC44451 structure
    GC44451Norfluoxetine (hydrochloride)
    CAS: 57226-68-3
    Purity: >98.00%

    Norfluoxetine (hydrochloride) est un métabolite actif de la fluoxétine produit dans le foie via N-déméthylation et présente une activité orale.

  • GC44492 structure
    GC44492O-Desmethyl Metoprolol
    CAS: 62572-94-5
    Purity: >99.00%

    O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol.