GLPBio

Seizure Disorders

Products Related to Seizure Disorders(93)

  • GC18176 structure
    GC181765α,6β-Dihydroxycholestanol
    CAS: 1253-84-5
    Purity: >98%

    5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase.

  • GC18336 structure
    GC18336Gabaculine (hydrochloride)
    CAS: 59556-17-1
    Purity: >95.00%

    An irreversible inhibitor of GABA-T

  • GC18399 structure
    GC18399Ethotoin
    CAS: 86-35-1
    Purity: >98.00%

    Ethotoin est un anticonvulsivant hydantoïne.

  • GC18505 structure
    GC18505Carisbamate
    CAS: 194085-75-1
    Purity: >98%

    Le carisbamate (RWJ-333369) est un neuromodulateur actif par voie orale.

  • GC18511 structure
    GC18511Picrotoxin
    CAS: 124-87-8
    Purity: >98%

    Picrotoxin (Cocculin) est un alcaloïde végétal qui agit en tant qu'un antagoniste non-compétitif des récepteurs GABAA et peut bloquer le canal chlorure des récepteurs GABAA.

  • GC18596 structure
    GC18596(±)-2-propyl-4-Pentenoic Acid
    CAS: 1575-72-0
    Purity: >98.00%

    L'acide (±)-2-propyl-4-penténoÏque (4-en-VPA) est un métabolite toxique majeur de l'acide valproÏque.

  • GC18707 structure
    GC18707Pimprinine
    CAS: 13640-26-1
    Purity: >98%

    Pimprinine is an alkaloid originally isolated from Streptomyces that has diverse biological activities, including anticonvulsant, antiplatelet, and antimicrobial properties.

  • GC18783 structure
    GC1878313,14-dihydro-15-keto Prostaglandin E1
    CAS: 5094-14-4
    Purity: >98.00%

    13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity.

  • GC19926 structure
    GC19926Methyl malonic acid
    CAS: 108-59-8
    Purity: >99.50%
  • GC20029 structure
    GC20029L(-)-Borneol
    CAS: 464-45-9
    Purity: >98.00%
  • GC39293 structure
    GC39293ICA-27243
    CAS: 325457-89-4
    Purity: >99.00%

    ICA-27243 est un ouvreur de canal potassique KCNQ2/Q3 sélectif, puissant et actif par voie orale avec une CE50 de 0,38 μM.

  • GC39342 structure
    GC39342AZD7325
    CAS: 942437-37-8
    Purity: >98.50%

    AZD7325 est un PAM sélectif partiel puissant et actif par voie orale des récepteurs GABAAα2 et Aα3 (Ki = 0,3 et 1,3 nM, respectivement), et a une efficacité antagoniste moindre sur les sous-types de récepteurs Aα1 et Aα5 .

  • GC40196 structure
    GC40196Levetiracetam-d6
    CAS: 1133229-30-7
    Purity: >99.50%

    Levetiracetam-d6 est un dérivé deutérié de Levetiracetam, un composé stable marqué aux isotopes contenant 6 atomes de deutérium.

  • GC40286 structure
    GC40286(E,Z)-2-propyl-2-Pentenoic Acid
    CAS: 60218-41-9
    Purity: >98.00%

    (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.

  • GC40848 structure
    GC40848Aspalatone
    CAS: 147249-33-0
    Purity: >98.00%

    Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism.

  • GC40951 structure
    GC40951L-Allylglycine
    CAS: 16338-48-0
    Purity: >98.00%

    L-Allylglycine est un inhibiteur de la glutamate décarboxylase (GAD) qui réduit la biosynthèse de GABA dans le cerveau.

  • GC42553 structure
    GC425535-hydroxy-Nω-methyl Tryptamine (oxalate)
    CAS: 15558-50-6
    Purity: >95.00%

    5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants.

  • GC42881 structure
    GC42881Avermectin B1a aglycone
    CAS: 71828-14-3
    Purity: >95.00%

    Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a.

  • GC43391 structure
    GC43391Decanoic Acid (sodium salt)
    CAS: 1002-62-6
    Purity: >95.00%

    Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons.

  • GC43450 structure
    GC43450Dieldrin
    CAS: 60-57-1
    Purity: 95.00%

    Dieldrin is an organochlorine insecticide and an antagonist of GABAA receptors (IC50 = 3.27 μM in rat brain vesicles).

  • GC43568 structure
    GC43568DPDPE (trifluoroacetate salt)
    Purity: >95.00%

    DPDPE is a synthetic enkephalin peptide and δ-opioid receptor agonist (Ki = 2.7 nM in rat brain homogenates).

  • GC43821 structure
    GC43821Hexadecanamide
    CAS: 629-54-9
    Purity: >98.00%

    Hexadecanamide is a primary fatty acid amide that is derived from palmitic acid (C16:0) and belongs to a class of important cell signaling lipids.

  • GC44298 structure
    GC44298N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid
    CAS: 24967-27-9
    Purity: >98.00%

    N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid est un inhibiteur efficace de la sialidase (néuraminidase) mammifère.

  • GC44732 structure
    GC44732Protopine (hydrochloride)
    CAS: 6164-47-2
    Purity: >98.00%

    Protopine is an alkaloid found in Berberidaceae, Ranunculaceae, Rutaceae, Fumariaceae, and Papaveraceae with diverse biological activities.