TK05 |
| Catalog No.GC65438 |
TK05 est un inhibiteur puissant et sélectif de la leucotriène C4 synthase (LTC4S) avec une IC50 de 95 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1245734-61-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM[1].
TK05 reduces LTC4 production in a dose-dependent manner with an IC50 value of 318 ± 60 nM in MM6 Cells[1].
TK05 (0.12-6 mg/kg; given i.p.; only once) significantly reduces LTE4 levels[1].
[1]. Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase. J Pharmacol Exp Ther. 2015 Oct;355(1):108-16.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *