GLPBio

Frunexian

Catalog No.: GC73668Purity:>97.00%Synonyms: EP-7041
Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa.

Products are for research use only. Not for human use. We do not sell to patients.


Frunexian
Cas No.: 1803270-60-1
1 mgIn Stock
$194.00
1
5 mgIn Stock
$486.00
1

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    35, 97–116 (2025)
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Description

Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research[1].


References:
[1]. Pollack CV Jr, et al. EP-7041, a Factor XIa Inhibitor as a Potential Antithrombotic Strategy in Extracorporeal Membrane Oxygenation: A Brief Report. Crit Care Explor. 2020 Sep 15;2(9):e0196.

Product Documents

Purity:>97.00%Appearance:A solid

Chemical Properties

CAS No.
1803270-60-1
Synonyms
EP-7041
Molecular Formula
C19H26N4O4
Molecular Weight
374.43
Solubility
DMSO : 100 mg/mL (267.07 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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