GLPBio

G7-18NATE TFA

Catalog No.: GC74311Purity:>98.00%
COASDSData Sheet
G7-18NATE TFA is a peptide inhibitor of Grb7.

Products are for research use only. Not for human use. We do not sell to patients.

G7-18NATE TFA
1 mgIn Stock
$50.00
1
5 mgIn Stock
$126.00
1
10 mgIn Stock
$198.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines.

G7-18NATE (10 μM, 24 h) inhibits cell migration in MDA-MB-468 cells[2].

References:
[1]. Sang J, et al. Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity. Molecules. 2019 Oct 17;24(20):3739.
[2]. Giricz O, et al. GRB7 is required for triple-negative breast cancer cell invasion and survival. Breast Cancer Res Treat. 2012 Jun;133(2):607-15.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Molecular Formula
C67H80N14O19S.xC2HF3O2
Molecular Weight
1417.50 (free base)
Solubility
DMSO : 100 mg/mL (Need ultrasonic)
Storage
Sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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