GLPBio

1,3-Bis-(Z-Leu-Leu)-diaminoacetone

Catalog No.: GA20367Purity:>98%
(Z-LL)? Ketone, cysteine protease inhibitor that specifically and efficiently inhibits processing of the p-Prl signal peptide (IC?? ca. 50 nM) without affecting the activities of signal peptidases and other proteases such as lysosomal cathepsins and proteasome.

Products are for research use only. Not for human use. We do not sell to patients.


1,3-Bis-(Z-Leu-Leu)-diaminoacetone
Cas No.: 313664-40-3
5mgIn Stock
$183.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

(Z-LL) Ketone, cysteine protease inhibitor that specifically and efficiently inhibits processing of the p-Prl signal peptide (IC50 ca. 50 nM) without affecting the activities of signal peptidases and other proteases such as lysosomal cathepsins and pro

Chemical Properties

CAS No.
313664-40-3
Molecular Formula
C43H64N6O9
Molecular Weight
809
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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