H-Tyr-Lys-OH |
Catalog No.GA22981
One-Click Copy Product Info
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H-Tyr-Lys-OH is a dipeptide that can serve as a biomarker for AJH-1. H-Tyr-Lys-OH has a good binding affinity with angiotensin-converting enzyme (ACE).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 54925-88-1
Sample solution is provided at 25 µL, 10mM.
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H-Tyr-Lys-OH is a dipeptide that can serve as a biomarker for AJH-1. H-Tyr-Lys-OH has a good binding affinity with angiotensin-converting enzyme (ACE)[1]. Dipeptides are commonly used to study enzyme mechanisms, protein synthesis and degradation processes, and signaling pathways[2]. H-Tyr-Lys-OH consists of two amino acid residues, tyrosine (Tyr) and lysine (Lys). Tyrosine contains a phenol group, which makes it important in protein interactions and enzyme catalysis[3]. The side chain of lysine contains an amino group that can form hydrogen bonds with other molecules, participating in various biochemical reactions[4].
References:
[1] Mikolasch A, et al. Laccase-catalyzed cross-linking of amino acids and peptides with dihydroxylated aromatic compounds[J]. Amino acids, 2010, 39: 671-683.
[2] Li M, Wei Y, Feng Z, et al. Dipeptides VL increase protein accumulation in C2C12 cells by activating the Akt-mTOR pathway and inhibiting the NF-κB pathway[J]. Food Bioscience, 2022, 45: 101493.
[3] Radi R. Protein tyrosine nitration: biochemical mechanisms and structural basis of functional effects[J]. Accounts of chemical research, 2013, 46(2): 550-559.
[4] Damodaran S. Amino acids, peptides and proteins[J]. Fennema’s food chemistry, 2008, 4: 425-439.
| Cas No. | 54925-88-1 | SDF | |
| Formula | C15H23N3O4 | M.Wt | 309.37 |
| Solubility | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.2324 mL | 16.1619 mL | 32.3238 mL |
| 5 mM | 646.5 μL | 3.2324 mL | 6.4648 mL |
| 10 mM | 323.2 μL | 1.6162 mL | 3.2324 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)