GLPBio

Ganglioside GM2

Catalog No.: GC73167Purity:>98.00%
Ganglioside GM2 is a human tumor antigen (OFA-I-1).

Products are for research use only. Not for human use. We do not sell to patients.


Ganglioside GM2
Cas No.: 127663-77-8
1 mgIn Stock
$898.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease.

References:
[1]. Tai T, et al. Ganglioside GM2 as a human tumor antigen (OFA-I-1). Proc Natl Acad Sci U S A. 1983 Sep;80(17):5392-6.
[2]. Anheuser S, et al. Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity. J Lipid Res. 2015 Sep;56(9):1747-61.
[3]. Nakamura K, et al. Dissection and optimization of immune effector functions of humanized anti-ganglioside GM2 monoclonal antibody. Mol Immunol. 2000 Dec;37(17):1035-46.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
127663-77-8
Molecular Formula
C67H121N3O26
Molecular Weight
1384.68
Solubility
DMSO : 14 mg/mL (10.11 mM; Need ultrasonic and warming)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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