BMS-983970 is an oral pan-Notch inhibitor for the treatment of cancer.
[1]. Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer. Cancer Res October 1, 2014 74; 1643
BMS-983970
Catalog No.: GC35537Purity:>99.00%
BMS-983970 is an oral pan-Notch inhibitor for the treatment of multiplecancers.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1584713-87-0
10mM (in 1mL DMSO)In Stock
$370.00
1
2mgIn Stock
$216.00
1
5mgIn Stock
$324.00
1
10mgIn Stock
$464.00
1
50mgIn Stock
$1,391.00
1
100mgIn Stock
$1,947.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $370.00 | In Stock | 1 | |
| 2mg | $216.00 | In Stock | 1 | |
| 5mg | $324.00 | In Stock | 1 | |
| 10mg | $464.00 | In Stock | 1 | |
| 50mg | $1,391.00 | In Stock | 1 | |
| 100mg | $1,947.00 | In Stock | 1 |
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Citations
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Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.00%Appearance:A solid
Chemical Properties
CAS No.
1584713-87-0
SMILES
O=C(N[C@@H]1C(NC2=C(F)C=CC=C2C(C3=CC=CC=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CC4CC4)C(N)=O
Molecular Formula
C26H26F4N4O3
Molecular Weight
518.5
Solubility
DMSO: ≥ 50 mg/mL (96.43 mM); Water: < 0.1 mg/mL (insoluble)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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