Btk inhibitor 1 is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122.
[1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122.
Btk inhibitor 1
Catalog No.: GC35561Purity:>98.00%
Btk inhibitor 1 is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1412418-47-3
10mM (in 1mL DMSO)In Stock
$51.00
1
5mgIn Stock
$59.00
1
10mgIn Stock
$86.00
1
25mgIn Stock
$157.00
1
50mgIn Stock
$223.00
1
100mgIn Stock
$319.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $51.00 | In Stock | 1 | |
| 5mg | $59.00 | In Stock | 1 | |
| 10mg | $86.00 | In Stock | 1 | |
| 25mg | $157.00 | In Stock | 1 | |
| 50mg | $223.00 | In Stock | 1 | |
| 100mg | $319.00 | In Stock | 1 |
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Nature641, 529–536 (2025)
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Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
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Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
1412418-47-3
SMILES
NC1=C2C(N(C3CNCCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1
Molecular Formula
C22H22N6O
Molecular Weight
386.45
Solubility
DMSO: 50 mg/mL (129.38 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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