Angiogenesis
Research Areas
Products Related to Angiogenesis(378)
- GC10140Thrombin Receptor Agonist PeptideCAS: 137339-65-2Purity: >98%
Thrombin Receptor Agonist Peptide is a synthetic thrombin receptor agonist peptide.
- GC13559CilengitideCAS: 188968-51-6Purity: >99.00%
Cilengitide, a cyclized pentapeptide, is a potent integrins antagonist with IC 50 values of 0.61nM, 8.4nM and 14.9nM for ανβ3, ανβ5, and α5β1, respectively.
- GC14540SLIGKV-NH2CAS: 190383-13-2Purity: >98.00%
SLIGKV-NH2 (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
- GC15192A 286982CAS: 280749-17-9Purity: >98.00%
A 286982 is a potent, nonpeptide inhibitors of leukocyte function-associated antigen-1/ intracellular adhesion molecule-1 (LFA-1/ICAM-1) interaction, with IC 50 values of 44 and 35nM in LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively.
- GC15817PAR-4 Agonist Peptide, amide (AY-NH2)CAS: 352017-71-1Purity: >98%
PAR-4 Agonist Peptide, amide(AY-NH2) (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
- GC17514SLIGRL-NH2CAS: 171436-38-7Purity: >99.50%
SLIGRL-NH2 is a specific protease-activated receptor 2 (PAR2) agonist with an EC 50 value of approximately 10μM. SLIGRL-NH2 does not activate PAR1.
- GA21303Cyclo(Arg-Gly-Asp-D-Phe-Cys)CAS: 862772-11-0Purity: >99.00%
Cyclo(Arg-Gly-Asp-D-Phe-Cys), commonly abbreviated as cRGDfC, is a cyclic RGD peptide that shows high affinity and selectivity for the integrin αvβ3 .
- GA23350PAR-3 (1-6) amide (human)CAS: 1872435-09-0Purity: >98%
PAR-3 (1-6) amide (human) is a proteinase-activated receptor (PAR-3) agonist peptide.
- GC10046Molidustat (BAY85-3934)CAS: 1154028-82-6Purity: >99.00%
Molidustat (BAY85-3934) (BAY 85-3934) is a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with mean IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3.
- GC10235Plinabulin (NPI-2358)CAS: 714272-27-2Purity: >98.00%
Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9.8 nM against HT-29 cells. Plinabulin (NPI-2358) binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells.
- GC10291SCH 79797 dihydrochlorideCAS: 1216720-69-2Purity: >98.00%
SCH 79797 dihydrochloride is an efficient and selective non-peptide proteinase-activated receptor 1 (PAR1) antagonist, with an IC 50 of 70nM and a Ki of 35nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10048 | MNS | 1485-00-3 | >98% | |
Inhibitor of Src/Syk tyrosine kinases | ||||
| GC10140 | Thrombin Receptor Agonist Peptide | 137339-65-2 | >98% | |
Thrombin Receptor Agonist Peptide is a synthetic thrombin receptor agonist peptide. | ||||
| GC11230 | RN486 | 1242156-23-5 | >99.50% | |
Btk inhibitor,potent and selective | ||||
| GC11662 | TRAP-6 | 141136-83-6 | >99.50% | |
TRAP-6 is a selective protease-activated receptor 1 (PAR1) agonist composed of six amino acids. | ||||
| GC11727 | VKGILS-NH2 | 942413-05-0 | >99.50% | |
control peptide for SLIGKV-NH2, PAR1 agonist | ||||
| GC11951 | PAR 4 (1-6) | 225779-44-2 | >98% | |
PAR4 agonist | ||||
| GC13227 | LRGILS-NH2 | 245329-01-5 | >98% | |
Protease-activated receptor agonist | ||||
| GC13559 | Cilengitide | 188968-51-6 | >99.00% | |
Cilengitide, a cyclized pentapeptide, is a potent integrins antagonist with IC 50 values of 0.61nM, 8.4nM and 14.9nM for ανβ3, ανβ5, and α5β1, respectively. | ||||
| GC14540 | SLIGKV-NH2 | 190383-13-2 | >98.00% | |
SLIGKV-NH2 (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide. | ||||
| GC14831 | AC 264613 | 1051487-82-1 | >95.00% | |
PAR2 agonist,potent and selective | ||||
| GC15192 | A 286982 | 280749-17-9 | >98.00% | |
A 286982 is a potent, nonpeptide inhibitors of leukocyte function-associated antigen-1/ intracellular adhesion molecule-1 (LFA-1/ICAM-1) interaction, with IC 50 values of 44 and 35nM in LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively. | ||||
| GC15290 | AC 55541 | 916170-19-9 | >98.50% | |
PAR2 agonist,potent and selective | ||||
| GC15557 | A 205804 | 251992-66-2 | >98.00% | |
A 205804 is a potent and selective lead inhibitor of E-selectin and ICAM-1 expression (E-selectin: IC 50 = 20nM; ICAM-1: IC 50 = 25nM). | ||||
| GC15817 | PAR-4 Agonist Peptide, amide (AY-NH2) | 352017-71-1 | >98% | |
PAR-4 Agonist Peptide, amide(AY-NH2) (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. | ||||
| GC17368 | 2-Furoyl-LIGRLO-amide | 729589-58-6 | >99.50% | |
Protease-activated receptor agonist | ||||
| GC17444 | TFLLR-NH2 | 197794-83-5 | >98% | |
PAR1 selective agonist | ||||
| GC17514 | SLIGRL-NH2 | 171436-38-7 | >99.50% | |
SLIGRL-NH2 is a specific protease-activated receptor 2 (PAR2) agonist with an EC 50 value of approximately 10μM. SLIGRL-NH2 does not activate PAR1. | ||||
| GC17560 | BIO 1211 | 187735-94-0 | >98.00% | |
BIO 1211 is an α4β1 (VLA-4) integrin inhibitor, which inhibits α4β1 (IC₅₀=4nM) and α4β7 (IC₅₀=2μM) . | ||||
| GC17991 | RLLFT-NH2 | 447408-68-6 | >98% | |
Protease-activated receptor agonist | ||||
| GA21303 | Cyclo(Arg-Gly-Asp-D-Phe-Cys) | 862772-11-0 | >99.00% | |
Cyclo(Arg-Gly-Asp-D-Phe-Cys), commonly abbreviated as cRGDfC, is a cyclic RGD peptide that shows high affinity and selectivity for the integrin αvβ3 . | ||||
| GA23350 | PAR-3 (1-6) amide (human) | 1872435-09-0 | >98% | |
PAR-3 (1-6) amide (human) is a proteinase-activated receptor (PAR-3) agonist peptide. | ||||
| GC10046 | Molidustat (BAY85-3934) | 1154028-82-6 | >99.00% | |
Molidustat (BAY85-3934) (BAY 85-3934) is a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with mean IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3. | ||||
| GC10235 | Plinabulin (NPI-2358) | 714272-27-2 | >98.00% | |
Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9.8 nM against HT-29 cells. Plinabulin (NPI-2358) binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells. | ||||
| GC10291 | SCH 79797 dihydrochloride | 1216720-69-2 | >98.00% | |
SCH 79797 dihydrochloride is an efficient and selective non-peptide proteinase-activated receptor 1 (PAR1) antagonist, with an IC 50 of 70nM and a Ki of 35nM. | ||||
