GLPBio

Calcitriol Derivatives

Catalog No.: GC35590Purity:>98.00%
Calcitriol Derivatives is a vitamin D3 analog.

Products are for research use only. Not for human use. We do not sell to patients.


Calcitriol Derivatives
Cas No.: 2070009-24-2
1mgIn Stock
$759.00
1
5mgIn Stock
$2,845.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Calcitriol Derivatives is a vitamin D3 analog. v

[1]. Barrera D, Noyola-MartÍnez N, Avila E, Halhali A, Larrea F, DÍaz L.Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions.Cytokine. 2012 Mar;57(3):316-21. [2]. Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y.Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis.Am J Nephrol. 2012;35(1):58-68. [3]. Michalak K, Wicha J.Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione.J Org Chem. 2011 Aug 19;76(16):6906-11. [4]. Moorthi RN, Kandula P, Moe SM.Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question.Curr Opin Nephrol Hypertens. 2011 Jul;20(4):354-9. [5]. Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS.Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system.Cell Cycle. 2010 Aug 1;9(15):3022-9.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
2070009-24-2
SMILES
O[C@H](C/1=C)C[C@@H](CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C)(O)C)C)([H])[C@]3(C)CCC\2)OCCC#N
Molecular Formula
C30H47NO3
Molecular Weight
469.7
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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