GLPBio

Omadacycline mesylate

Catalog No.: GC36804Purity:>98%Synonyms: PTK 0796 mesylate; Amadacycline mesylate
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics.

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Omadacycline mesylate
Cas No.: 1196800-40-4
2mgIn Stock
$148.00
1
5mgIn Stock
$241.00
1
10mgIn Stock
$417.00
1
50mgIn Stock
$1,391.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Omadacycline mesylate is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.IC50 Value: N/ATarget: Antibacterialin vitro: in vivo: Clinical trial: Phase III Study to Compare the Safety and Efficacy of PTK-0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI).

[1]. Schmitz J, Holzgrabe U. Amadacyclin - a new tetracycline antibiotic in the pipeline. Pharm Unserer Zeit. 2010 Mar;39(2):94-5.

Chemical Properties

CAS No.
1196800-40-4
Synonyms
PTK 0796 mesylate; Amadacycline mesylate
SMILES
CS(=O)(O)=O.O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(CNCC(C)(C)C)C=C4N(C)C)N
Molecular Formula
C30H44N4O10S
Molecular Weight
652.76
Solubility
Soluble in DMSO
Storage
4°C, protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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