GLPBio

PTP1B-IN-1

Catalog No.: GC37037Purity:>98.50%
COASDSData Sheet
PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis.

Products are for research use only. Not for human use. We do not sell to patients.

PTP1B-IN-1
Cas No.: 612530-44-6
10mM (in 1mL DMSO)In Stock
$280.00
1
1mgIn Stock
$120.00
1
5mgIn Stock
$252.00
1
10mgIn Stock
$378.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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Description

PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis.

[1]. Black E, et al. Structure-based design of protein tyrosine phosphatase-1B inhibitors. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. [2]. Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19(7):2145-55.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
612530-44-6
SMILES
O=S(N1C2=CC=CC=C2)(NC(C1)=O)=O
Molecular Formula
C8H8N2O3S
Molecular Weight
212.23
Solubility
DMSO: ≥ 38 mg/mL (179.05 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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