GLPBio

Saikosaponin B3

Catalog No.: GC37582Purity:>98%
COASDSData Sheet
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L.

Products are for research use only. Not for human use. We do not sell to patients.

Saikosaponin B3
Cas No.: 58316-42-0
1mgIn Stock
$45.00
1
5mgIn Stock
$99.00
1
10mgIn Stock
$162.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells[1][2][3].

[1]. Jang MJ, et al. Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. Molecules. 2014 Dec 4;19(12):20340-9. [2]. Kita T, et al. Analgesic and other pharmacologic actions of saiko-saponin in repeated cold stressed (SART stressed) animals. J Pharmacobiodyn. 1980 Jun;3(6):269-80. [3]. Kimura Y, et al. Effects of saikosaponins on the metabolic actions of adrenaline, ACTH and insulin on the fat cells. Chem Pharm Bull (Tokyo). 1980 Jun;28(6):1788-94.

Chemical Properties

CAS No.
58316-42-0
SMILES
C[C@]12[C@@]([C@@H](C=C3[C@]2(C[C@H](O)[C@]4(CO)[C@@]3([H])CC(C)(C)CC4)C)OC)([H])[C@@]5([C@@]([C@@](C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@@H](O)[C@@H](C)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O)CC5)CO)([H])CC1)C
Molecular Formula
C43H72O14
Molecular Weight
813.02
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for Saikosaponin B3

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%