GLPBio

D-Tetrahydropalmatine

Catalog No.: GC38228Purity:>98.00%Synonyms: (+)-Corydalis B, (+)-Tetrahydropalmatine, (R)-Tetrahydropalmatine, D-THP
COASDSData Sheet
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis.

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D-Tetrahydropalmatine
Cas No.: 3520-14-7
10mM (in 1mL DMSO)In Stock
$92.00
1
1mgIn Stock
$32.00
1
5mgIn Stock
$83.00
1
10mgIn Stock
$141.00
1
20mgIn Stock
$240.00
1
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Description

D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis[1]. D-Tetrahydropalmatine is a Dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors[2]. D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor[3].

[1]. Ma ZJ, et al. [Effects of different types and standard of processing vinegaron inherent constituents in rhizoma of Corydalis yanhusuo]. Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):465-7. [2]. Xu SX, et al. Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo Yao Li Xue Bao. 1989 Mar;10(2):104-10. [3]. Tu M, et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important rolein its hepatotoxicity. Toxicology. 2013 Sep 15;311(3):225-30.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
3520-14-7
Synonyms
(+)-Corydalis B, (+)-Tetrahydropalmatine, (R)-Tetrahydropalmatine, D-THP
SMILES
COC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@@]3([H])C2)=C1OC
Molecular Formula
C21H25NO4
Molecular Weight
355.43
Solubility
Soluble in DMSO
Storage
Store at 2-8°C,protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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