PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC)[1].
[1]. Robert A. Volkmann, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1.
PPC-NB
Catalog No.: GC38348Purity:>98%
PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1887040-81-4
50mgIn Stock
$169.00
1
100mgIn Stock
$270.00
1
250mgIn Stock
$405.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 50mg | $169.00 | In Stock | 1 | |
| 100mg | $270.00 | In Stock | 1 | |
| 250mg | $405.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
1887040-81-4
SMILES
O=C(OCC(SSC1=NC=CC=C1)C)OC2=CC=C([N+]([O-])=O)C=C2
Molecular Formula
C15H14N2O5S2
Molecular Weight
366.41
Solubility
DMSO : 100 mg/mL (272.92 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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