GLPBio

Febrifugine

Catalog No.: GC38614Purity:>98.50%Synonyms: (+)-Febrifugine, NSC 315535
COASDSData Sheet
Febrifugine is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga, with antimalarial activity .

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Febrifugine
Cas No.: 24159-07-7
1mgIn Stock
$36.00
1
5mgIn Stock
$153.00
1
10mgIn Stock
$270.00
1
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Description

Febrifugine is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga, with antimalarial activity [1].

[1]. Herman JD, et al. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20;7(288):288ra77. [2]. McLaughlin NP, et al. The chemistry and biology of febrifugine and halofuginone. Bioorg Med Chem. 2014 Apr 1;22(7):1993-2004.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
24159-07-7
Synonyms
(+)-Febrifugine, NSC 315535
SMILES
O=C1N(CC(C[C@H]2NCCC[C@@H]2O)=O)C=NC3=C1C=CC=C3
Molecular Formula
C16H19N3O3
Molecular Weight
301.34
Solubility
DMF: 1.5 mg/ml,DMSO: 3.0 mg/ml,Ethanol: 0.1 mg/ml,PBS (pH 7.2): 2.5 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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