GLPBio

DNA31

Catalog No.: GC35888Purity:>98.00%
COASDSData Sheet
DNA31 is a potent RNA polymerase inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

DNA31
Cas No.: 845626-57-5
1mgIn Stock
$180.00
1
5mgIn Stock
$450.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

DNA31 is the 31 worldwide most common mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. DNA31 is used for a first level genetic test to the neonatal screening protocol for cystic fibrosis (CF)[1].

[1]. Narzi L, et al. Does cystic fibrosis neonatal screening detect atypical CF forms• Extended genetic characterization and 4-year clinical follow-up. Clin Genet. 2007 Jul;72(1):39-46.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
845626-57-5
SMILES
O=C1C2=C(O[C@@]1(O/C=C\[C@]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@@H](O)[C@@H](C)/C=C/C=C(C)/C3=O)C)O)C)OC(C)=O)C)([H])OC)C)C(C)=C(O)C4=C2C(C(OC5=CC(N6CCC(N)CC6)=C7)=C(N3)C4=O)=NC5=C7O
Molecular Formula
C48H58N4O13
Molecular Weight
898.99
Solubility
DMSO : 5 mg/mL (5.56 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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