YW1159 (Synonyms: Compound 3d) |
| Catalog No.GC45597 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2131223-69-1
Sample solution is provided at 25 µL, 10mM.
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YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.1,2 It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.2
References
2. Obianom, O.N., Ai, Y., Li, Y., et al. Triazole-based inhibitors of the Wnt/β-catenin signaling pathway improve glucose and lipid metabolism in diet-induced obese mice. J. Med. Chem. 62(2), 727-741 (2019).
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