GLPBio

(-)-KCC2 blocker 1

Catalog No.: GC83579Purity:>99.00%
COASDSData Sheet
(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1.

Products are for research use only. Not for human use. We do not sell to patients.

(-)-KCC2 blocker 1
Cas No.: 1228439-73-3
10mM (in 1mL DMSO)In Stock
$173.00
1
1mgIn Stock
$63.00
1
5mgIn Stock
$158.00
1
10mgIn Stock
$230.00
1
25mgIn Stock
$504.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1. KCC2 blocker 1 (compound 13) is an orally active and selective K + -Cl - cotransporter KCC2 blocker with an IC50 of 1 μM [1].

References:
[1]. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1228439-73-3
Molecular Formula
C22H25NO5S
Molecular Weight
415.5
Solubility
DMSO: 100 mg/mL (240.67 mM; Need ultrasonic)
Storage
Store at 4°C, sealed storage, away from moisture and light
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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