Methyl 13-cis-4-oxoretinoate (Compound 4b) is a retinoic acid receptors (RARs) agonist. Methyl 13-cis-4-oxoretinoate is promising for research of dermatological diseases (e.g., disorders related to abnormal differentiation of keratinocytes) and cancers[1].
References:
[1].TANAKA H, et al. Specific oxidation of retinoic acid to 4-oxo-retinoic acid in diluted acid solutions[J]. Chemical and pharmaceutical bulletin, 1995, 43(2): 356-358.
















