GLPBio

GLUT4 activator 2

Catalog No.: GC74074
GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases.

Products are for research use only. Not for human use. We do not sell to patients.


GLUT4 activator 2
Cas No.: 2761446-81-3
5 mgIn Stock
$54.00
1
10 mgIn Stock
$86.00
1
25 mgIn Stock
$176.00
1
50 mgIn Stock
$284.00
1
100 mgIn Stock
$450.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation.

References:
[1]. Yin TC, et al. Insulin sensitization by small molecules enhancing GLUT4 translocation. Cell Chem Biol. 2023 Aug 17;30(8):933-942.e6.

Product Documents

Appearance:A solid

Chemical Properties

CAS No.
2761446-81-3
Molecular Formula
C16H18Cl2N2O
Molecular Weight
325.23
Solubility
DMSO : 125 mg/mL (384.34 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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