GPR109A

GPR109A (also known as hydroxycarboxylic acid receptor 2) is a nicotinic acid/niacin and (D)-beta-hydroxybutyrate receptor. It conveys acid-induced apoptosis in matureneutrophils and may lead to neutrophilapoptosis after niacin activation.

Products Related to GPR109A(4)

GC15653 PF-05212384 (PKI-587)
CAS: 1197160-78-3
Purity: >98.00%
PF-05212384 (PKI-587) is a potent dual PI3K/mTOR inhibitor, exhibiting inhibitory effects against PI3Kα (IC₅₀=0.4nM), PI3Kβ (IC₅₀=6nM), PI3Kγ (IC₅₀=8nM), PI3Kδ (IC₅₀=6nM), and mTOR (IC₅₀=1.4nM).
GC15006 MK-6892
CAS: 917910-45-3
Purity: >99.00%
GC32464 MK-0354
CAS: 851776-28-8
Purity: >99.00%
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b.
GC74667 GPR109 receptor agonist-2
CAS: 957129-38-3
Purity: >99.00%
GPR109 receptor agonist-2 (Compound 5) is a selective GPR109a agonist with a pEC50 of 5.53.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC15653	PF-05212384 (PKI-587)	1197160-78-3	>98.00%
GC15653	PF-05212384 (PKI-587) is a potent dual PI3K/mTOR inhibitor, exhibiting inhibitory effects against PI3Kα (IC₅₀=0.4nM), PI3Kβ (IC₅₀=6nM), PI3Kγ (IC₅₀=8nM), PI3Kδ (IC₅₀=6nM), and mTOR (IC₅₀=1.4nM).
GC15006	MK-6892	917910-45-3	>99.00%
GC32464	MK-0354	851776-28-8	>99.00%
GC32464	MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b.
GC74667	GPR109 receptor agonist-2	957129-38-3	>99.00%
GC74667	GPR109 receptor agonist-2 (Compound 5) is a selective GPR109a agonist with a pEC50 of 5.53.