Guanadrel is an antihypertensive agent.1 In vivo, guanadrel (5 mg/kg) inhibits reflex increases in mean arterial and femoral perfusion blood pressures induced by bilateral carotid occlusion in dogs. Formulations containing guanadrel have been used in the treatment of hypertension.
1.Finnerty, F.A., Jr., and Brogden, R.N.Guanadrel. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in hypertensionDrugs30(1)22-31(1985)